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Full 3D Microwave Breast Imaging Using a Deep-Learning Technique

A deep learning technique to enhance 3D images of the complex-valued permittivity of the breast obtained via microwave imaging is investigated. The developed technique is an extension of one created to enhance 2D images. We employ a 3D Convolutional Neural Network, based on the U-Net architecture, t...

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Autores principales: Khoshdel, Vahab, Asefi, Mohammad, Ashraf, Ahmed, LoVetri, Joe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8321110/
https://www.ncbi.nlm.nih.gov/pubmed/34460695
http://dx.doi.org/10.3390/jimaging6080080
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author Khoshdel, Vahab
Asefi, Mohammad
Ashraf, Ahmed
LoVetri, Joe
author_facet Khoshdel, Vahab
Asefi, Mohammad
Ashraf, Ahmed
LoVetri, Joe
author_sort Khoshdel, Vahab
collection PubMed
description A deep learning technique to enhance 3D images of the complex-valued permittivity of the breast obtained via microwave imaging is investigated. The developed technique is an extension of one created to enhance 2D images. We employ a 3D Convolutional Neural Network, based on the U-Net architecture, that takes in 3D images obtained using the Contrast-Source Inversion (CSI) method and attempts to produce the true 3D image of the permittivity. The training set consists of 3D CSI images, along with the true numerical phantom images from which the microwave scattered field utilized to create the CSI reconstructions was synthetically generated. Each numerical phantom varies with respect to the size, number, and location of tumors within the fibroglandular region. The reconstructed permittivity images produced by the proposed 3D U-Net show that the network is not only able to remove the artifacts that are typical of CSI reconstructions, but it also enhances the detectability of the tumors. We test the trained U-Net with 3D images obtained from experimentally collected microwave data as well as with images obtained synthetically. Significantly, the results illustrate that although the network was trained using only images obtained from synthetic data, it performed well with images obtained from both synthetic and experimental data. Quantitative evaluations are reported using Receiver Operating Characteristics (ROC) curves for the tumor detectability and RMS error for the enhancement of the reconstructions.
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spelling pubmed-83211102021-08-26 Full 3D Microwave Breast Imaging Using a Deep-Learning Technique Khoshdel, Vahab Asefi, Mohammad Ashraf, Ahmed LoVetri, Joe J Imaging Article A deep learning technique to enhance 3D images of the complex-valued permittivity of the breast obtained via microwave imaging is investigated. The developed technique is an extension of one created to enhance 2D images. We employ a 3D Convolutional Neural Network, based on the U-Net architecture, that takes in 3D images obtained using the Contrast-Source Inversion (CSI) method and attempts to produce the true 3D image of the permittivity. The training set consists of 3D CSI images, along with the true numerical phantom images from which the microwave scattered field utilized to create the CSI reconstructions was synthetically generated. Each numerical phantom varies with respect to the size, number, and location of tumors within the fibroglandular region. The reconstructed permittivity images produced by the proposed 3D U-Net show that the network is not only able to remove the artifacts that are typical of CSI reconstructions, but it also enhances the detectability of the tumors. We test the trained U-Net with 3D images obtained from experimentally collected microwave data as well as with images obtained synthetically. Significantly, the results illustrate that although the network was trained using only images obtained from synthetic data, it performed well with images obtained from both synthetic and experimental data. Quantitative evaluations are reported using Receiver Operating Characteristics (ROC) curves for the tumor detectability and RMS error for the enhancement of the reconstructions. MDPI 2020-08-11 /pmc/articles/PMC8321110/ /pubmed/34460695 http://dx.doi.org/10.3390/jimaging6080080 Text en © 2020 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ).
spellingShingle Article
Khoshdel, Vahab
Asefi, Mohammad
Ashraf, Ahmed
LoVetri, Joe
Full 3D Microwave Breast Imaging Using a Deep-Learning Technique
title Full 3D Microwave Breast Imaging Using a Deep-Learning Technique
title_full Full 3D Microwave Breast Imaging Using a Deep-Learning Technique
title_fullStr Full 3D Microwave Breast Imaging Using a Deep-Learning Technique
title_full_unstemmed Full 3D Microwave Breast Imaging Using a Deep-Learning Technique
title_short Full 3D Microwave Breast Imaging Using a Deep-Learning Technique
title_sort full 3d microwave breast imaging using a deep-learning technique
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8321110/
https://www.ncbi.nlm.nih.gov/pubmed/34460695
http://dx.doi.org/10.3390/jimaging6080080
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