Mycobacterium tuberculosis inhibits the NLRP3 inflammasome activation via its phosphokinase PknF

Mycobacterium tuberculosis (Mtb) has evolved to evade host innate immunity by interfering with macrophage functions. Interleukin-1β (IL-1β) is secreted by macrophages after the activation of the inflammasome complex and is crucial for host defense against Mtb infections. We have previously shown tha...

Descripción completa

Detalles Bibliográficos
Autores principales: Rastogi, Shivangi, Ellinwood, Sarah, Augenstreich, Jacques, Mayer-Barber, Katrin D., Briken, Volker
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8321130/
https://www.ncbi.nlm.nih.gov/pubmed/34324582
http://dx.doi.org/10.1371/journal.ppat.1009712

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8321130/
https://www.ncbi.nlm.nih.gov/pubmed/34324582
http://dx.doi.org/10.1371/journal.ppat.1009712

Ejemplares similares