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Mycobacterium tuberculosis inhibits the NLRP3 inflammasome activation via its phosphokinase PknF
Mycobacterium tuberculosis (Mtb) has evolved to evade host innate immunity by interfering with macrophage functions. Interleukin-1β (IL-1β) is secreted by macrophages after the activation of the inflammasome complex and is crucial for host defense against Mtb infections. We have previously shown tha...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8321130/ https://www.ncbi.nlm.nih.gov/pubmed/34324582 http://dx.doi.org/10.1371/journal.ppat.1009712 |