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Complete corporeal preservation clitoroplasty: new insights into feminizing genitoplasty

INTRODUCTION: 46,XX Congenital adrenal hyperplasia (CAH) remains the first cause of genital virilization and current surgical techniques aim to restore female aspect of genitalia while preserving dorsal neurovascular bundle but not at the expense of not preserving erectile tissue. We aim to report o...

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Autores principales: Fernandez, Nicolas, Chavarriaga, Julián, Pérez, Jaime
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Urologia 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8321476/
https://www.ncbi.nlm.nih.gov/pubmed/33848081
http://dx.doi.org/10.1590/S1677-5538.IBJU.2020.0839
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author Fernandez, Nicolas
Chavarriaga, Julián
Pérez, Jaime
author_facet Fernandez, Nicolas
Chavarriaga, Julián
Pérez, Jaime
author_sort Fernandez, Nicolas
collection PubMed
description INTRODUCTION: 46,XX Congenital adrenal hyperplasia (CAH) remains the first cause of genital virilization and current surgical techniques aim to restore female aspect of genitalia while preserving dorsal neurovascular bundle but not at the expense of not preserving erectile tissue. We aim to report our experience with a new surgical technique for clitoroplasty, completely preserving corporeal bodies, neurovascular bundles without dismembering the clitoris, in four patients with over a year follow up. MATERIALS AND METHODS: After IRB approval four patients with 46,XX CAH and Prader 5 and 3 external genitalia, underwent feminizing genitoplasty. Complete preservation of erectile tissue was accomplished without a need to dissect dorsal neurovascular bundle. Glans size allowed no need for glanular reduction and there was no need to dismember the corporeal bodies. RESULTS: Four patients 12 to 24-months-old underwent complete corporeal preservation clitoroplasty (CCPC), mean age was 18.5 months, mean follow up was 10.25 months. Vaginoplasty was performed in all patients with partial urogenital mobilization (PUM) and Urogenital Sinus flap (UF), only one severely virilized patient required a parasagittal pre-rectal approach to mobilize the vagina. We had no complications until last follow up. CONCLUSION: To our knowledge, we are introducing the concept of CCPC without the need of disassembling the corporeal bodies, neurovascular bundle and glans. It stands as a new alternative for feminizing genitoplasty with complete preservation of erectile tissue and no dissection of neurovascular bundle. Although there is still lacking long-term follow-up, it represents a new step in conservative reconfiguration of the external virilized female genitalia.
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spelling pubmed-83214762021-08-06 Complete corporeal preservation clitoroplasty: new insights into feminizing genitoplasty Fernandez, Nicolas Chavarriaga, Julián Pérez, Jaime Int Braz J Urol Surgical Technique INTRODUCTION: 46,XX Congenital adrenal hyperplasia (CAH) remains the first cause of genital virilization and current surgical techniques aim to restore female aspect of genitalia while preserving dorsal neurovascular bundle but not at the expense of not preserving erectile tissue. We aim to report our experience with a new surgical technique for clitoroplasty, completely preserving corporeal bodies, neurovascular bundles without dismembering the clitoris, in four patients with over a year follow up. MATERIALS AND METHODS: After IRB approval four patients with 46,XX CAH and Prader 5 and 3 external genitalia, underwent feminizing genitoplasty. Complete preservation of erectile tissue was accomplished without a need to dissect dorsal neurovascular bundle. Glans size allowed no need for glanular reduction and there was no need to dismember the corporeal bodies. RESULTS: Four patients 12 to 24-months-old underwent complete corporeal preservation clitoroplasty (CCPC), mean age was 18.5 months, mean follow up was 10.25 months. Vaginoplasty was performed in all patients with partial urogenital mobilization (PUM) and Urogenital Sinus flap (UF), only one severely virilized patient required a parasagittal pre-rectal approach to mobilize the vagina. We had no complications until last follow up. CONCLUSION: To our knowledge, we are introducing the concept of CCPC without the need of disassembling the corporeal bodies, neurovascular bundle and glans. It stands as a new alternative for feminizing genitoplasty with complete preservation of erectile tissue and no dissection of neurovascular bundle. Although there is still lacking long-term follow-up, it represents a new step in conservative reconfiguration of the external virilized female genitalia. Sociedade Brasileira de Urologia 2021-01-10 /pmc/articles/PMC8321476/ /pubmed/33848081 http://dx.doi.org/10.1590/S1677-5538.IBJU.2020.0839 Text en https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Surgical Technique
Fernandez, Nicolas
Chavarriaga, Julián
Pérez, Jaime
Complete corporeal preservation clitoroplasty: new insights into feminizing genitoplasty
title Complete corporeal preservation clitoroplasty: new insights into feminizing genitoplasty
title_full Complete corporeal preservation clitoroplasty: new insights into feminizing genitoplasty
title_fullStr Complete corporeal preservation clitoroplasty: new insights into feminizing genitoplasty
title_full_unstemmed Complete corporeal preservation clitoroplasty: new insights into feminizing genitoplasty
title_short Complete corporeal preservation clitoroplasty: new insights into feminizing genitoplasty
title_sort complete corporeal preservation clitoroplasty: new insights into feminizing genitoplasty
topic Surgical Technique
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8321476/
https://www.ncbi.nlm.nih.gov/pubmed/33848081
http://dx.doi.org/10.1590/S1677-5538.IBJU.2020.0839
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