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Can extended upper pole ureterectomy prevent ureteral stump syndrome after proximal approach for duplex kidneys?

INTRODUCTION: Symptomatic duplex kidneys usually present with recurrent urinary tract infection due to ureteral obstruction (megaureter, ureterocele or ectopic ureter) and/or vesicoureteral reflux. Upper-pole nephrectomy is a widely accepted procedure to correct symptomatic duplex systems with poor...

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Autores principales: Cezarino, Bruno Nicolino, Lopes, Roberto Iglesias, Berjeaut, Ricardo Haidar, Dénes, Francisco Tibor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Urologia 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8321497/
https://www.ncbi.nlm.nih.gov/pubmed/33848075
http://dx.doi.org/10.1590/S1677-5538.IBJU.2020.0686
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author Cezarino, Bruno Nicolino
Lopes, Roberto Iglesias
Berjeaut, Ricardo Haidar
Dénes, Francisco Tibor
author_facet Cezarino, Bruno Nicolino
Lopes, Roberto Iglesias
Berjeaut, Ricardo Haidar
Dénes, Francisco Tibor
author_sort Cezarino, Bruno Nicolino
collection PubMed
description INTRODUCTION: Symptomatic duplex kidneys usually present with recurrent urinary tract infection due to ureteral obstruction (megaureter, ureterocele or ectopic ureter) and/or vesicoureteral reflux. Upper-pole nephrectomy is a widely accepted procedure to correct symptomatic duplex systems with poor functioning moieties, also known as upper or proximal approach. The distal ureteral stump syndrome (DUSS) can be a late complication of this approach. There is no consensus upon the length of ureteral dissection and the better approach to symptomatic disease in duplex systems, so we aim to identify if extended ureteral dissection can prevent DUSS in top-down approach. MATERIALS AND METHODS: Forty-four consecutive patients with symptomatic duplex system were retrospectively classified into two groups: those with limited ureteral excision after heminephrectomy (HN) (group-1) and those with extended ureterectomy after HN (group-2). Patients were followed-up for at least 36 months regarding outcomes of distal ureteral stump. RESULTS: Overall complication was 20%. A total of 8 patients required unplanned further surgery in Group-1 (30%) whereas only 1 patient required unplanned surgery in group 2 (6%) (p=0.07). Subgroup analysis showed that Group-1 presented more DUSS requiring surgery during follow-up than group-2 (p=0.04). Factors possibly affecting complications incidence (such as ureterocele or ectopic ureter) did not differ between groups (p=0.72 and p=0.78). CONCLUSION: Upper pole nephrectomy should be performed with extended distal ureteral dissection to prevent ureteral stump complications.
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spelling pubmed-83214972021-08-06 Can extended upper pole ureterectomy prevent ureteral stump syndrome after proximal approach for duplex kidneys? Cezarino, Bruno Nicolino Lopes, Roberto Iglesias Berjeaut, Ricardo Haidar Dénes, Francisco Tibor Int Braz J Urol Original Article INTRODUCTION: Symptomatic duplex kidneys usually present with recurrent urinary tract infection due to ureteral obstruction (megaureter, ureterocele or ectopic ureter) and/or vesicoureteral reflux. Upper-pole nephrectomy is a widely accepted procedure to correct symptomatic duplex systems with poor functioning moieties, also known as upper or proximal approach. The distal ureteral stump syndrome (DUSS) can be a late complication of this approach. There is no consensus upon the length of ureteral dissection and the better approach to symptomatic disease in duplex systems, so we aim to identify if extended ureteral dissection can prevent DUSS in top-down approach. MATERIALS AND METHODS: Forty-four consecutive patients with symptomatic duplex system were retrospectively classified into two groups: those with limited ureteral excision after heminephrectomy (HN) (group-1) and those with extended ureterectomy after HN (group-2). Patients were followed-up for at least 36 months regarding outcomes of distal ureteral stump. RESULTS: Overall complication was 20%. A total of 8 patients required unplanned further surgery in Group-1 (30%) whereas only 1 patient required unplanned surgery in group 2 (6%) (p=0.07). Subgroup analysis showed that Group-1 presented more DUSS requiring surgery during follow-up than group-2 (p=0.04). Factors possibly affecting complications incidence (such as ureterocele or ectopic ureter) did not differ between groups (p=0.72 and p=0.78). CONCLUSION: Upper pole nephrectomy should be performed with extended distal ureteral dissection to prevent ureteral stump complications. Sociedade Brasileira de Urologia 2021-02-28 /pmc/articles/PMC8321497/ /pubmed/33848075 http://dx.doi.org/10.1590/S1677-5538.IBJU.2020.0686 Text en https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Cezarino, Bruno Nicolino
Lopes, Roberto Iglesias
Berjeaut, Ricardo Haidar
Dénes, Francisco Tibor
Can extended upper pole ureterectomy prevent ureteral stump syndrome after proximal approach for duplex kidneys?
title Can extended upper pole ureterectomy prevent ureteral stump syndrome after proximal approach for duplex kidneys?
title_full Can extended upper pole ureterectomy prevent ureteral stump syndrome after proximal approach for duplex kidneys?
title_fullStr Can extended upper pole ureterectomy prevent ureteral stump syndrome after proximal approach for duplex kidneys?
title_full_unstemmed Can extended upper pole ureterectomy prevent ureteral stump syndrome after proximal approach for duplex kidneys?
title_short Can extended upper pole ureterectomy prevent ureteral stump syndrome after proximal approach for duplex kidneys?
title_sort can extended upper pole ureterectomy prevent ureteral stump syndrome after proximal approach for duplex kidneys?
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8321497/
https://www.ncbi.nlm.nih.gov/pubmed/33848075
http://dx.doi.org/10.1590/S1677-5538.IBJU.2020.0686
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