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PNKP is required for maintaining the integrity of progenitor cell populations in adult mice

DNA repair proteins are critical to the maintenance of genomic integrity. Specific types of genotoxic factors, including reactive oxygen species generated during normal cellular metabolism or as a result of exposure to exogenous oxidative agents, frequently leads to “ragged” single-strand DNA breaks...

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Detalles Bibliográficos
Autores principales:	Shin, Wisoo, Alpaugh, Whitney, Hallihan, Laura J, Sinha, Sarthak, Crowther, Emilie, Martin, Gary R, Scheidl-Yee, Teresa, Yang, Xiaoyan, Yoon, Grace, Goldsmith, Taylor, Berger, Nelson D, de Almeida, Luiz GN, Dufour, Antoine, Dobrinski, Ina, Weinfeld, Michael, Jirik, Frank R, Biernaskie, Jeff
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Life Science Alliance LLC 2021
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8321660/ https://www.ncbi.nlm.nih.gov/pubmed/34226276 http://dx.doi.org/10.26508/lsa.202000790

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