CNKSR1 serves as a scaffold to activate an EGFR phosphatase via exclusive interaction with RhoB-GTP

Epidermal growth factor receptor (EGFR) and human EGFR 2 (HER2) phosphorylation drives HER2-positive breast cancer cell proliferation. Enforced activation of phosphatases for those receptors could be a therapeutic option for HER2-positive breast cancers. Here, we report that degradation of an endoso...

Descripción completa

Detalles Bibliográficos
Autores principales: Nishiyama, Kanako, Maekawa, Masashi, Nakagita, Tomoya, Nakayama, Jun, Kiyoi, Takeshi, Chosei, Mami, Murakami, Akari, Kamei, Yoshiaki, Takeda, Hiroyuki, Takada, Yasutsugu, Higashiyama, Shigeki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8321701/
https://www.ncbi.nlm.nih.gov/pubmed/34187934
http://dx.doi.org/10.26508/lsa.202101095

Ejemplares similares

Ejemplares similares