Cargando…

The Heterogeneity of Infiltrating Macrophages in Metastatic Osteosarcoma and Its Correlation with Immunotherapy

BACKGROUND: Metastatic osteosarcoma is a common and fatal bone tumor. Several studies have found that tumor-infiltrating immune cells play pivotal roles in the progression of metastatic osteosarcoma. However, the heterogeneity of infiltrating immune cells across metastatic and primary osteosarcoma r...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Zhanchao, Wu, Huiqiao, Chen, Yu, Chen, Huajiang, Yuan, Wen, Wang, Xinwei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8321719/ https://www.ncbi.nlm.nih.gov/pubmed/34335756 http://dx.doi.org/10.1155/2021/4836292

Ejemplares similares

Lactobacillus paracasei S16 Alleviates Lumbar Disc Herniation by Modulating Inflammation Response and Gut Microbiota
por: Wang, Zhanchao, et al.
Publicado: (2021)

Macrophages in Osteosarcoma Immune Microenvironment: Implications for Immunotherapy
por: Luo, Zhong-Wei, et al.
Publicado: (2020)

Anterior cervical discectomy and fusion, open-door laminoplasty, or laminectomy with fusion: Which is the better treatment for four-level cervical spondylotic myelopathy?
por: Zhong, Huajian, et al.
Publicado: (2023)

PODN is a prognostic biomarker and correlated with immune infiltrates in osteosarcoma
por: Yao, Feng, et al.
Publicado: (2021)

Application of a new integrated low-profile anterior plate and cage system in single-level cervical spondylosis: a preliminary retrospective study
por: Wei, Leixin, et al.
Publicado: (2022)

Infiltration of LPAR5(+) macrophages in osteosarcoma tumor microenvironment predicts better outcomes
por: He, Yi, et al.
Publicado: (2022)

Identification of key serum biomarkers for the diagnosis and metastatic prediction of osteosarcoma by analysis of immune cell infiltration
por: Chen, Zhihao, et al.
Publicado: (2022)

Dysregulation of macrophage polarization is associated with the metastatic process in osteosarcoma
por: Dumars, Clotilde, et al.
Publicado: (2016)

EVI2B Is a Prognostic Biomarker and Is Correlated with Monocyte and Macrophage Infiltration in Osteosarcoma Based on an Integrative Analysis
por: Dai, Zhenlin, et al.
Publicado: (2023)

Identification of MAP3K15 as a potential prognostic biomarker and correlation with immune infiltrates in osteosarcoma
por: Chen, Zhuning, et al.
Publicado: (2021)

Model for predicting immunotherapy based on M2 macrophage infiltration in TNBC
por: Wu, Haoming, et al.
Publicado: (2023)

Infiltration of Apoptotic M2 Macrophage Subpopulation Is Negatively Correlated with the Immunotherapy Response in Colorectal Cancer
por: Liu, Rui, et al.
Publicado: (2022)

Novel Immunotherapies for Osteosarcoma
por: Lu, Yubao, et al.
Publicado: (2022)

Prognostic Implications of the Complement Protein C1Q and Its Correlation with Immune Infiltrates in Osteosarcoma
por: Huang, Hanji, et al.
Publicado: (2021)

Exceptional response to PD-1 inhibition immunotherapy in advanced metastatic osteosarcoma with tumor site infection
por: Li, Meng, et al.
Publicado: (2022)

Comprehensive analysis of fatty acid and lactate metabolism–related genes for prognosis value, immune infiltration, and therapy in osteosarcoma patients
por: Wu, Zhouwei, et al.
Publicado: (2022)

GNPNAT1 is a potential biomarker correlated with immune infiltration and immunotherapy outcome in breast cancer
por: Yuan, Renjie, et al.
Publicado: (2023)

The Cancer-Associated Fibroblasts-Related Gene COMP Is a Novel Predictor for Prognosis and Immunotherapy Efficacy and Is Correlated with M2 Macrophage Infiltration in Colon Cancer
por: Ma, He, et al.
Publicado: (2022)

The hexosamine biosynthesis pathway-related gene signature correlates with immune infiltration and predicts prognosis of patients with osteosarcoma
por: Su, Zexin, et al.
Publicado: (2022)

Increased PD-L1 and T-cell infiltration in the presence of HLA class I expression in metastatic high-grade osteosarcoma: a rationale for T-cell-based immunotherapy
por: Sundara, Yayan T., et al.
Publicado: (2016)

MYCBP2 expression correlated with inflammatory cell infiltration and prognosis immunotherapy in thyroid cancer patients
por: Wang, Guilin, et al.
Publicado: (2022)

Modulation of immunosuppressive cells and noncoding RNAs as immunotherapy in osteosarcoma
por: Xia, Yidan, et al.
Publicado: (2022)

Increased M1 Macrophages Infiltration Correlated With Poor Survival Outcomes and Radiation Response in Gliomas
por: Zhou, Zhaoming, et al.
Publicado: (2020)

Tantalum–Zirconium Co‐Doped Metal–Organic Frameworks Sequentially Sensitize Radio–Radiodynamic–Immunotherapy for Metastatic Osteosarcoma
por: Li, Tao, et al.
Publicado: (2023)

BMPR2 expression level is correlated with low immune infiltration and predicts metastasis and poor survival in osteosarcoma
por: Cao, Hongxin, et al.
Publicado: (2021)

Identification of prognostic biomarkers associated with metastasis and immune infiltration in osteosarcoma
por: Yang, Bingsheng, et al.
Publicado: (2021)

CXCR3 from chemokine receptor family correlates with immune infiltration and predicts poor survival in osteosarcoma
por: Tang, Yin, et al.
Publicado: (2019)

Mixed Response to Cancer Immunotherapy is Driven by Intratumor Heterogeneity and Differential Interlesion Immune Infiltration
por: Morinaga, Takao, et al.
Publicado: (2022)

Exploring the molecular mechanisms of osteosarcoma by the integrated analysis of mRNAs and miRNA microarrays
por: Shen, Hao, et al.
Publicado: (2018)

Modelling the spatial heterogeneity and molecular correlates of lymphocytic infiltration in triple-negative breast cancer
por: Yuan, Yinyin
Publicado: (2015)

POLE and Mismatch Repair Status, Checkpoint Proteins and Tumor-Infiltrating Lymphocytes in Combination, and Tumor Differentiation: Identify Endometrial Cancers for Immunotherapy
por: Dong, Dandan, et al.
Publicado: (2021)

Metastatic Spread of Osteosarcoma
por: Price, C. H. G., et al.
Publicado: (1973)

The metastatic patterns of osteosarcoma.
por: Jeffree, G. M., et al.
Publicado: (1975)

Microglia response following acute demyelination is heterogeneous and limits infiltrating macrophage dispersion
por: Plemel, Jason R., et al.
Publicado: (2020)

RNA adenosine modifications related to prognosis and immune infiltration in osteosarcoma
por: Chen, Shijie, et al.
Publicado: (2022)

Smurf1 Facilitates Oxidative Stress and Fibrosis of Ligamentum Flavum by Promoting Nrf2 Ubiquitination and Degradation
por: Gu, Yifei, et al.
Publicado: (2023)

Protective Prognostic Biomarkers Negatively Correlated with Macrophage M2 Infiltration in Low-Grade Glioma
por: Zhu, Yunyang, et al.
Publicado: (2022)

Changes in cell shape are correlated with metastatic potential in murine and human osteosarcomas
por: Lyons, Samanthe M., et al.
Publicado: (2016)

SFTPA1 is a potential prognostic biomarker correlated with immune cell infiltration and response to immunotherapy in lung adenocarcinoma
por: Yuan, Lu, et al.
Publicado: (2021)

T-Cell-Based Immunotherapy for Osteosarcoma: Challenges and Opportunities
por: Wang, Zhan, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_7jevc35n1t4o6mv6obb677q4eq