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An Integrated Analysis of Dostarlimab Immunogenicity
Monoclonal antibodies that block the interaction between programmed cell death 1 (PD-1) and its ligand (PD-L1) have revolutionized cancer immunotherapy. However, immunogenic responses to these new therapies—such as the development of antidrug antibodies (ADAs) and neutralizing antibodies (NAbs)—may...
Autores principales: | Lu, Sharon, Bowsher, Ronald R., Clancy, Amanda, Rosen, Amy, Zhang, Mingxuan, Yang, Ying, Koeck, Kathleen, Gao, Minggeng, Potocka, Elizabeth, Guo, Wei, Jen, Kai Yu, Im, Ellie, Milton, Ashley |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8321970/ https://www.ncbi.nlm.nih.gov/pubmed/34324079 http://dx.doi.org/10.1208/s12248-021-00624-7 |
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