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Probing tissue transglutaminase mediated vascular smooth muscle cell aging using a novel transamidation-deficient Tgm2-C277S mouse model

Tissue transglutaminase (TG2), a multifunctional protein of the transglutaminase family, has putative transamidation-independent functions in aging-associated vascular stiffening and dysfunction. Developing preclinical models will be critical to fully understand the physiologic relevance of TG2’s tr...

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Detalles Bibliográficos
Autores principales:	Wang, Huilei, Chen, James, Jandu, Sandeep, Melucci, Sean, Savage, William, Nandakumar, Kavitha, Kang, Sara K., Barreto-Ortiz, Sebastian, Poe, Alan, Rastogi, Shivam, Bauer, Maria, Steppan, Jochen, Santhanam, Lakshmi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8322091/ https://www.ncbi.nlm.nih.gov/pubmed/34326316 http://dx.doi.org/10.1038/s41420-021-00543-8

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