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Kras-driven intratumoral heterogeneity triggers infiltration of M2 polarized macrophages via the circHIPK3/PTK2 immunosuppressive circuit

Intratumoral heterogeneity in lung cancer is essential for evasion of immune surveillance by tumor cells and establishment of immunosuppression. Gathering data reveal that circular RNAs (circRNAs), play a role in the pathogenesis and progression of lung cancer. Particularly Kras-driven circRNA signa...

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Detalles Bibliográficos
Autores principales:	Katopodi, Theodora, Petanidis, Savvas, Domvri, Kalliopi, Zarogoulidis, Paul, Anestakis, Doxakis, Charalampidis, Charalampos, Tsavlis, Drosos, Bai, Chong, Huang, Haidong, Freitag, Lutz, Hohenforst-Schmidt, Wolfgang, Matthaios, Dimitris, Porpodis, Konstantinos
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8322174/ https://www.ncbi.nlm.nih.gov/pubmed/34326381 http://dx.doi.org/10.1038/s41598-021-94671-x

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