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Thymoquinone protects against cardiac mitochondrial DNA loss, oxidative stress, inflammation and apoptosis in isoproterenol-induced myocardial infarction in rats
INTRODUCTION: Myocardial infarction (MI) is an ischemic life-threatening disease with exaggerated oxidative stress state that vigorously damages the cardiomyocyte membrane and subcellular structures, including the vital mitochondrial DNA (mtDNA). The mtDNA is responsible for the proper functionality...
Autores principales: | Khalifa, Asmaa A., Rashad, Radwa M., El-Hadidy, Wessam F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8322274/ https://www.ncbi.nlm.nih.gov/pubmed/34355083 http://dx.doi.org/10.1016/j.heliyon.2021.e07561 |
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