MuSyC is a consensus framework that unifies multi-drug synergy metrics for combinatorial drug discovery

Drug combination discovery depends on reliable synergy metrics but no consensus exists on the correct synergy criterion to characterize combined interactions. The fragmented state of the field confounds analysis, impedes reproducibility, and delays clinical translation of potential combination treat...

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Detalles Bibliográficos
Autores principales: Wooten, David J., Meyer, Christian T., Lubbock, Alexander L. R., Quaranta, Vito, Lopez, Carlos F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8322415/
https://www.ncbi.nlm.nih.gov/pubmed/34326325
http://dx.doi.org/10.1038/s41467-021-24789-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8322415/
https://www.ncbi.nlm.nih.gov/pubmed/34326325
http://dx.doi.org/10.1038/s41467-021-24789-z

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