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MuSyC is a consensus framework that unifies multi-drug synergy metrics for combinatorial drug discovery
Drug combination discovery depends on reliable synergy metrics but no consensus exists on the correct synergy criterion to characterize combined interactions. The fragmented state of the field confounds analysis, impedes reproducibility, and delays clinical translation of potential combination treat...
Autores principales: | Wooten, David J., Meyer, Christian T., Lubbock, Alexander L. R., Quaranta, Vito, Lopez, Carlos F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8322415/ https://www.ncbi.nlm.nih.gov/pubmed/34326325 http://dx.doi.org/10.1038/s41467-021-24789-z |
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