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Pediatric Glaucoma in a University Hospital

AIMS AND OBJECTIVES: This study aimed at describing the characteristics and outcomes of pediatric glaucoma patients in a university hospital in Lebanon and comparing them between primary congenital glaucoma (PCG) and secondary glaucoma. MATERIALS AND METHODS: Sixty-four eyes of 40 pediatric glaucoma...

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Autores principales: Dakroub, Mohamad, Khair, Diana, Noureddine, Bahaa’, Al-Haddad, Christiane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Jaypee Brothers Medical Publishers 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8322597/
https://www.ncbi.nlm.nih.gov/pubmed/34393450
http://dx.doi.org/10.5005/jp-journals-10078-1291
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author Dakroub, Mohamad
Khair, Diana
Noureddine, Bahaa’
Al-Haddad, Christiane
author_facet Dakroub, Mohamad
Khair, Diana
Noureddine, Bahaa’
Al-Haddad, Christiane
author_sort Dakroub, Mohamad
collection PubMed
description AIMS AND OBJECTIVES: This study aimed at describing the characteristics and outcomes of pediatric glaucoma patients in a university hospital in Lebanon and comparing them between primary congenital glaucoma (PCG) and secondary glaucoma. MATERIALS AND METHODS: Sixty-four eyes of 40 pediatric glaucoma patients with a follow-up of 1 year or more were reviewed. Parameters were studied for both PCG and secondary glaucoma groups. Three major outcomes were considered: intraocular pressure (IOP) control, final best-corrected visual acuity (BCVA), and the proportion of failed angle surgeries. RESULTS: Sixty-four eyes were included divided into 29 PCG and 35 secondary glaucoma eyes, followed up for a mean of 6.6 ± 4.7 years. Eyes with PCG presented earlier, with a higher initial IOP and underwent earlier surgery than their secondary glaucoma counterparts. Although 85.9% of all eyes achieved good IOP control, 44.4% of them had a BCVA ≥20/50 with PCG having a better visual prognosis. Secondary glaucoma eyes needed more medications at the end of their follow-up. In this group, it was shown that a later age at first surgery, unilateral disease, and multiple surgeries were associated with a BCVA < 20/50. CONCLUSION: Patients with PCG presented earlier and with a higher IOP than secondary glaucoma; they were also operated on earlier. Both groups demonstrated good IOP control at the end of the follow-up period with PCG eyes having a superior visual outcome. Secondary glaucoma eyes required a higher number of medications at their final visit. In this population, multiple surgeries, unilateral disease, and a delayed first surgery conferred a poorer visual prognosis. CLINICAL SIGNIFICANCE: Data regarding the characteristics of pediatric glaucoma, especially in the Middle East, are scarce. Our study sheds the light on the presentation of different types of pediatric glaucoma and their outcomes namely IOP control and visual acuity. HOW TO CITE THIS ARTICLE: Dakroub M, Khair D, Noureddine B, et al. Pediatric Glaucoma in a University Hospital. J Curr Glaucoma Pract 2021;15(1):8–13.
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spelling pubmed-83225972021-08-12 Pediatric Glaucoma in a University Hospital Dakroub, Mohamad Khair, Diana Noureddine, Bahaa’ Al-Haddad, Christiane J Curr Glaucoma Pract Original Article AIMS AND OBJECTIVES: This study aimed at describing the characteristics and outcomes of pediatric glaucoma patients in a university hospital in Lebanon and comparing them between primary congenital glaucoma (PCG) and secondary glaucoma. MATERIALS AND METHODS: Sixty-four eyes of 40 pediatric glaucoma patients with a follow-up of 1 year or more were reviewed. Parameters were studied for both PCG and secondary glaucoma groups. Three major outcomes were considered: intraocular pressure (IOP) control, final best-corrected visual acuity (BCVA), and the proportion of failed angle surgeries. RESULTS: Sixty-four eyes were included divided into 29 PCG and 35 secondary glaucoma eyes, followed up for a mean of 6.6 ± 4.7 years. Eyes with PCG presented earlier, with a higher initial IOP and underwent earlier surgery than their secondary glaucoma counterparts. Although 85.9% of all eyes achieved good IOP control, 44.4% of them had a BCVA ≥20/50 with PCG having a better visual prognosis. Secondary glaucoma eyes needed more medications at the end of their follow-up. In this group, it was shown that a later age at first surgery, unilateral disease, and multiple surgeries were associated with a BCVA < 20/50. CONCLUSION: Patients with PCG presented earlier and with a higher IOP than secondary glaucoma; they were also operated on earlier. Both groups demonstrated good IOP control at the end of the follow-up period with PCG eyes having a superior visual outcome. Secondary glaucoma eyes required a higher number of medications at their final visit. In this population, multiple surgeries, unilateral disease, and a delayed first surgery conferred a poorer visual prognosis. CLINICAL SIGNIFICANCE: Data regarding the characteristics of pediatric glaucoma, especially in the Middle East, are scarce. Our study sheds the light on the presentation of different types of pediatric glaucoma and their outcomes namely IOP control and visual acuity. HOW TO CITE THIS ARTICLE: Dakroub M, Khair D, Noureddine B, et al. Pediatric Glaucoma in a University Hospital. J Curr Glaucoma Pract 2021;15(1):8–13. Jaypee Brothers Medical Publishers 2021 /pmc/articles/PMC8322597/ /pubmed/34393450 http://dx.doi.org/10.5005/jp-journals-10078-1291 Text en Copyright © 2021; Jaypee Brothers Medical Publishers (P) Ltd. https://creativecommons.org/licenses/by-nc/4.0/© Jaypee Brothers Medical Publishers. 2021 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted use, distribution, and non-commercial reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated.
spellingShingle Original Article
Dakroub, Mohamad
Khair, Diana
Noureddine, Bahaa’
Al-Haddad, Christiane
Pediatric Glaucoma in a University Hospital
title Pediatric Glaucoma in a University Hospital
title_full Pediatric Glaucoma in a University Hospital
title_fullStr Pediatric Glaucoma in a University Hospital
title_full_unstemmed Pediatric Glaucoma in a University Hospital
title_short Pediatric Glaucoma in a University Hospital
title_sort pediatric glaucoma in a university hospital
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8322597/
https://www.ncbi.nlm.nih.gov/pubmed/34393450
http://dx.doi.org/10.5005/jp-journals-10078-1291
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