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Comparison of Central Corneal Thickness Measurements by Contact and Non-contact Pachymetry Devices

AIM AND OBJECTIVE: To compare central corneal thickness (CCT) measurements obtained by handheld contact ultrasound pachymetry (HCUP) and non-contact pachymetry devices. MATERIALS AND METHODS: Ninety eyes of 90 patients (52 male and 38 female) were included in the study. Measurements from two non-con...

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Autores principales: Mayali, Huseyin, Altinisik, Muhammed, Diri, Ismail, Ilker, Sami, Kurt, Emin, Kayikcioglu, Ozcan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Jaypee Brothers Medical Publishers 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8322600/
https://www.ncbi.nlm.nih.gov/pubmed/34393453
http://dx.doi.org/10.5005/jp-journals-10078-1295
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author Mayali, Huseyin
Altinisik, Muhammed
Diri, Ismail
Ilker, Sami
Kurt, Emin
Kayikcioglu, Ozcan
author_facet Mayali, Huseyin
Altinisik, Muhammed
Diri, Ismail
Ilker, Sami
Kurt, Emin
Kayikcioglu, Ozcan
author_sort Mayali, Huseyin
collection PubMed
description AIM AND OBJECTIVE: To compare central corneal thickness (CCT) measurements obtained by handheld contact ultrasound pachymetry (HCUP) and non-contact pachymetry devices. MATERIALS AND METHODS: Ninety eyes of 90 patients (52 male and 38 female) were included in the study. Measurements from two non-contact devices, —specular microscopy (SM, Konan Medical, CA, USA) and Oculus Pentacam (Oculus Inc., Germany)—were compared against HCUP (Pachmate 2, DGH Technology, Inc, PA, USA). Ultrasound measurements were obtained 3 times by the same user and averaged. The differences were calculated by one-way ANOVA. Agreement between measurements were assessed by Bland–Altman plots and intraclass correlation coefficient tests. Coefficient of repeatability (%, CR) was defined as 1.96*standard deviations of the differences between pairs of measurements divided by the average of the means. RESULTS: The mean age was 34.31 ± 14.39 (14–74) years, and the mean intraocular pressure was 16.48 ± 2.63 mm Hg (12–21). Mean CCT measured by HCUP, SM, and Pentacam was 557.76 ± 36.76 μm, 550.29 ± 43.74 μm, and 541.41 ± 35.7 μm, respectively (p < 0.05). In the Bland–Altman plot, 95% limit of agreements were 19.5 and 14.18 μm among HCUP measurements, 34.55 μm between HCUP and Pentacam, 41.49 μm between SM and Pentacam, and 46.98 μm between HCUP and SM. CR values (%) were 3.49, 2.54, 6.28, 7.68, and 8.47, respectively. CONCLUSION: There were significant differences between the mean CCT values of the measurement devices. CLINICAL SIGNIFICANCE: Contact and non-contact devices may not interchangeable in the clinical assessment of CCT. HOW TO CITE THIS ARTICLE: Mayali H, Altinisik M, Diri I, et al. Comparison of Central Corneal Thickness Measurements by Contact and Non-contact Pachymetry Devices. J Curr Glaucoma Pract 2021;15(1):28–31.
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spelling pubmed-83226002021-08-12 Comparison of Central Corneal Thickness Measurements by Contact and Non-contact Pachymetry Devices Mayali, Huseyin Altinisik, Muhammed Diri, Ismail Ilker, Sami Kurt, Emin Kayikcioglu, Ozcan J Curr Glaucoma Pract Original Article AIM AND OBJECTIVE: To compare central corneal thickness (CCT) measurements obtained by handheld contact ultrasound pachymetry (HCUP) and non-contact pachymetry devices. MATERIALS AND METHODS: Ninety eyes of 90 patients (52 male and 38 female) were included in the study. Measurements from two non-contact devices, —specular microscopy (SM, Konan Medical, CA, USA) and Oculus Pentacam (Oculus Inc., Germany)—were compared against HCUP (Pachmate 2, DGH Technology, Inc, PA, USA). Ultrasound measurements were obtained 3 times by the same user and averaged. The differences were calculated by one-way ANOVA. Agreement between measurements were assessed by Bland–Altman plots and intraclass correlation coefficient tests. Coefficient of repeatability (%, CR) was defined as 1.96*standard deviations of the differences between pairs of measurements divided by the average of the means. RESULTS: The mean age was 34.31 ± 14.39 (14–74) years, and the mean intraocular pressure was 16.48 ± 2.63 mm Hg (12–21). Mean CCT measured by HCUP, SM, and Pentacam was 557.76 ± 36.76 μm, 550.29 ± 43.74 μm, and 541.41 ± 35.7 μm, respectively (p < 0.05). In the Bland–Altman plot, 95% limit of agreements were 19.5 and 14.18 μm among HCUP measurements, 34.55 μm between HCUP and Pentacam, 41.49 μm between SM and Pentacam, and 46.98 μm between HCUP and SM. CR values (%) were 3.49, 2.54, 6.28, 7.68, and 8.47, respectively. CONCLUSION: There were significant differences between the mean CCT values of the measurement devices. CLINICAL SIGNIFICANCE: Contact and non-contact devices may not interchangeable in the clinical assessment of CCT. HOW TO CITE THIS ARTICLE: Mayali H, Altinisik M, Diri I, et al. Comparison of Central Corneal Thickness Measurements by Contact and Non-contact Pachymetry Devices. J Curr Glaucoma Pract 2021;15(1):28–31. Jaypee Brothers Medical Publishers 2021 /pmc/articles/PMC8322600/ /pubmed/34393453 http://dx.doi.org/10.5005/jp-journals-10078-1295 Text en Copyright © 2021; Jaypee Brothers Medical Publishers (P) Ltd. https://creativecommons.org/licenses/by-nc/4.0/© Jaypee Brothers Medical Publishers. 2021 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted use, distribution, and non-commercial reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated.
spellingShingle Original Article
Mayali, Huseyin
Altinisik, Muhammed
Diri, Ismail
Ilker, Sami
Kurt, Emin
Kayikcioglu, Ozcan
Comparison of Central Corneal Thickness Measurements by Contact and Non-contact Pachymetry Devices
title Comparison of Central Corneal Thickness Measurements by Contact and Non-contact Pachymetry Devices
title_full Comparison of Central Corneal Thickness Measurements by Contact and Non-contact Pachymetry Devices
title_fullStr Comparison of Central Corneal Thickness Measurements by Contact and Non-contact Pachymetry Devices
title_full_unstemmed Comparison of Central Corneal Thickness Measurements by Contact and Non-contact Pachymetry Devices
title_short Comparison of Central Corneal Thickness Measurements by Contact and Non-contact Pachymetry Devices
title_sort comparison of central corneal thickness measurements by contact and non-contact pachymetry devices
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8322600/
https://www.ncbi.nlm.nih.gov/pubmed/34393453
http://dx.doi.org/10.5005/jp-journals-10078-1295
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