Thiamine mediated reversal of left ventricular dysfunction in patients with alcoholic cardiomyopathy

This study aimed to evaluate the effect of thiamine supplementation on left ventricular (LV) systolic function in patients of alcoholic cardiomyopathy(ACM) presenting with acute heart failure(HF). 11 newly diagnosed patients were included. They were treated with 3 days of intravenous(IV) therapy wit...

Descripción completa

Detalles Bibliográficos
Autores principales: Satish, Oruganti Sai, Shaik, Shabbir Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8322806/
https://www.ncbi.nlm.nih.gov/pubmed/34154766
http://dx.doi.org/10.1016/j.ihj.2021.03.013
_version_ 1783731133555408896
author Satish, Oruganti Sai
Shaik, Shabbir Ali
author_facet Satish, Oruganti Sai
Shaik, Shabbir Ali
author_sort Satish, Oruganti Sai
collection PubMed
description This study aimed to evaluate the effect of thiamine supplementation on left ventricular (LV) systolic function in patients of alcoholic cardiomyopathy(ACM) presenting with acute heart failure(HF). 11 newly diagnosed patients were included. They were treated with 3 days of intravenous(IV) therapy with thiamine followed by oral supplementation. LVEF was 30% at baseline which improved by 45% and 53% along with reduction in LV dimensions over 3 and 6 months respectively. The study suggests the benefit of thiamine supplementation on LVEF in ACM patients with HF.
format Online
Article
Text
id pubmed-8322806
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-83228062021-07-31 Thiamine mediated reversal of left ventricular dysfunction in patients with alcoholic cardiomyopathy Satish, Oruganti Sai Shaik, Shabbir Ali Indian Heart J Short Communication This study aimed to evaluate the effect of thiamine supplementation on left ventricular (LV) systolic function in patients of alcoholic cardiomyopathy(ACM) presenting with acute heart failure(HF). 11 newly diagnosed patients were included. They were treated with 3 days of intravenous(IV) therapy with thiamine followed by oral supplementation. LVEF was 30% at baseline which improved by 45% and 53% along with reduction in LV dimensions over 3 and 6 months respectively. The study suggests the benefit of thiamine supplementation on LVEF in ACM patients with HF. Elsevier 2021 2021-04-02 /pmc/articles/PMC8322806/ /pubmed/34154766 http://dx.doi.org/10.1016/j.ihj.2021.03.013 Text en © 2021 Cardiological Society of India. Published by Elsevier B.V. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Short Communication
Satish, Oruganti Sai
Shaik, Shabbir Ali
Thiamine mediated reversal of left ventricular dysfunction in patients with alcoholic cardiomyopathy
title Thiamine mediated reversal of left ventricular dysfunction in patients with alcoholic cardiomyopathy
title_full Thiamine mediated reversal of left ventricular dysfunction in patients with alcoholic cardiomyopathy
title_fullStr Thiamine mediated reversal of left ventricular dysfunction in patients with alcoholic cardiomyopathy
title_full_unstemmed Thiamine mediated reversal of left ventricular dysfunction in patients with alcoholic cardiomyopathy
title_short Thiamine mediated reversal of left ventricular dysfunction in patients with alcoholic cardiomyopathy
title_sort thiamine mediated reversal of left ventricular dysfunction in patients with alcoholic cardiomyopathy
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8322806/
https://www.ncbi.nlm.nih.gov/pubmed/34154766
http://dx.doi.org/10.1016/j.ihj.2021.03.013
work_keys_str_mv AT satishorugantisai thiaminemediatedreversalofleftventriculardysfunctioninpatientswithalcoholiccardiomyopathy
AT shaikshabbirali thiaminemediatedreversalofleftventriculardysfunctioninpatientswithalcoholiccardiomyopathy

Ejemplares similares