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Open surgical ablation of ventricular tachycardia: Utility and feasibility of contemporary mapping and ablation tools

BACKGROUND: Ventricular tachycardia (VT) catheter ablation success may be limited when transcutaneous epicardial access is contraindicated. Surgical ablation (SurgAbl) is an option, but ablation guidance is limited without simultaneously acquired electrophysiological data. OBJECTIVE: We describe our...

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Autores principales: Kunkel, Megan, Rothstein, Peter, Sauer, Peter, Zipse, Matthew M., Sandhu, Amneet, Tumolo, Alexis Z., Borne, Ryan T., Aleong, Ryan G., Cleveland, Joseph C., Fullerton, David, Pal, Jay D., Davies, Austin S., Lane, Curtis, Nguyen, Duy T., Sauer, William H., Tzou, Wendy S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8322924/
https://www.ncbi.nlm.nih.gov/pubmed/34337578
http://dx.doi.org/10.1016/j.hroo.2021.05.004
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author Kunkel, Megan
Rothstein, Peter
Sauer, Peter
Zipse, Matthew M.
Sandhu, Amneet
Tumolo, Alexis Z.
Borne, Ryan T.
Aleong, Ryan G.
Cleveland, Joseph C.
Fullerton, David
Pal, Jay D.
Davies, Austin S.
Lane, Curtis
Nguyen, Duy T.
Sauer, William H.
Tzou, Wendy S.
author_facet Kunkel, Megan
Rothstein, Peter
Sauer, Peter
Zipse, Matthew M.
Sandhu, Amneet
Tumolo, Alexis Z.
Borne, Ryan T.
Aleong, Ryan G.
Cleveland, Joseph C.
Fullerton, David
Pal, Jay D.
Davies, Austin S.
Lane, Curtis
Nguyen, Duy T.
Sauer, William H.
Tzou, Wendy S.
author_sort Kunkel, Megan
collection PubMed
description BACKGROUND: Ventricular tachycardia (VT) catheter ablation success may be limited when transcutaneous epicardial access is contraindicated. Surgical ablation (SurgAbl) is an option, but ablation guidance is limited without simultaneously acquired electrophysiological data. OBJECTIVE: We describe our SurgAbl experience utilizing contemporary electroanatomic mapping (EAM) among patients with refractory VT storm. METHODS: Consecutive patients with recurrent VT despite antiarrhythmic drugs (AADs) and prior ablation, for whom percutaneous epicardial access was contraindicated, underwent open SurgAbl using intraoperative EAM guidance. RESULTS: Eight patients were included, among whom mean age was 63 ± 5 years, all were male, mean left ventricular ejection fraction was 39% ± 12%, and 2 (25%) had ischemic cardiomyopathy. Reasons for surgical epicardial access included dense adhesions owing to prior cardiac surgery, hemopericardium, or pericarditis (n = 6); or planned left ventricular assist device (LVAD) implantation at time of SurgAbl (n = 2). Cryoablation guided by real-time EAM was performed in all. Goals of clinical VT noninducibility or core isolation were achieved in 100%. VT burden was significantly reduced, from median 15 to 0 events in the month pre- and post-SurgAbl (P = .01). One patient underwent orthotopic heart transplantation for recurrent VT storm 2 weeks post-SurgAbl. Over mean follow-up of 3.4 ± 1.7 years, VT storm–free survival was achieved in 6 (75%); all continued AADs, although at lower dose. CONCLUSION: Surgical mapping and ablation of refractory VT with use of contemporary EAM is feasible and effective, particularly among patients with contraindication to percutaneous epicardial access or with another indication for cardiac surgery.
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spelling pubmed-83229242021-07-31 Open surgical ablation of ventricular tachycardia: Utility and feasibility of contemporary mapping and ablation tools Kunkel, Megan Rothstein, Peter Sauer, Peter Zipse, Matthew M. Sandhu, Amneet Tumolo, Alexis Z. Borne, Ryan T. Aleong, Ryan G. Cleveland, Joseph C. Fullerton, David Pal, Jay D. Davies, Austin S. Lane, Curtis Nguyen, Duy T. Sauer, William H. Tzou, Wendy S. Heart Rhythm O2 Clinical BACKGROUND: Ventricular tachycardia (VT) catheter ablation success may be limited when transcutaneous epicardial access is contraindicated. Surgical ablation (SurgAbl) is an option, but ablation guidance is limited without simultaneously acquired electrophysiological data. OBJECTIVE: We describe our SurgAbl experience utilizing contemporary electroanatomic mapping (EAM) among patients with refractory VT storm. METHODS: Consecutive patients with recurrent VT despite antiarrhythmic drugs (AADs) and prior ablation, for whom percutaneous epicardial access was contraindicated, underwent open SurgAbl using intraoperative EAM guidance. RESULTS: Eight patients were included, among whom mean age was 63 ± 5 years, all were male, mean left ventricular ejection fraction was 39% ± 12%, and 2 (25%) had ischemic cardiomyopathy. Reasons for surgical epicardial access included dense adhesions owing to prior cardiac surgery, hemopericardium, or pericarditis (n = 6); or planned left ventricular assist device (LVAD) implantation at time of SurgAbl (n = 2). Cryoablation guided by real-time EAM was performed in all. Goals of clinical VT noninducibility or core isolation were achieved in 100%. VT burden was significantly reduced, from median 15 to 0 events in the month pre- and post-SurgAbl (P = .01). One patient underwent orthotopic heart transplantation for recurrent VT storm 2 weeks post-SurgAbl. Over mean follow-up of 3.4 ± 1.7 years, VT storm–free survival was achieved in 6 (75%); all continued AADs, although at lower dose. CONCLUSION: Surgical mapping and ablation of refractory VT with use of contemporary EAM is feasible and effective, particularly among patients with contraindication to percutaneous epicardial access or with another indication for cardiac surgery. Elsevier 2021-05-11 /pmc/articles/PMC8322924/ /pubmed/34337578 http://dx.doi.org/10.1016/j.hroo.2021.05.004 Text en © 2021 Heart Rhythm Society. Published by Elsevier Inc. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Clinical
Kunkel, Megan
Rothstein, Peter
Sauer, Peter
Zipse, Matthew M.
Sandhu, Amneet
Tumolo, Alexis Z.
Borne, Ryan T.
Aleong, Ryan G.
Cleveland, Joseph C.
Fullerton, David
Pal, Jay D.
Davies, Austin S.
Lane, Curtis
Nguyen, Duy T.
Sauer, William H.
Tzou, Wendy S.
Open surgical ablation of ventricular tachycardia: Utility and feasibility of contemporary mapping and ablation tools
title Open surgical ablation of ventricular tachycardia: Utility and feasibility of contemporary mapping and ablation tools
title_full Open surgical ablation of ventricular tachycardia: Utility and feasibility of contemporary mapping and ablation tools
title_fullStr Open surgical ablation of ventricular tachycardia: Utility and feasibility of contemporary mapping and ablation tools
title_full_unstemmed Open surgical ablation of ventricular tachycardia: Utility and feasibility of contemporary mapping and ablation tools
title_short Open surgical ablation of ventricular tachycardia: Utility and feasibility of contemporary mapping and ablation tools
title_sort open surgical ablation of ventricular tachycardia: utility and feasibility of contemporary mapping and ablation tools
topic Clinical
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8322924/
https://www.ncbi.nlm.nih.gov/pubmed/34337578
http://dx.doi.org/10.1016/j.hroo.2021.05.004
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