The emerging role of gut microbiota in cardiovascular diseases

There is mounting evidence which suggests the involvement of gut microbiota dysbiosis in the pathogenesis of various cardiovascular diseases (CVD) and associated risk states such as hypertension, type 2 diabetes, obesity and dyslipidaemia, atherosclerosis, heart failure and atrial fibrillation. The...

Descripción completa

Detalles Bibliográficos
Autores principales: Kumar, Dilip, Mukherjee, Sanjeev S., Chakraborty, Rabin, Roy, Rana Rathod, Pandey, Arindam, Patra, Soumya, Dey, Somnath
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8322927/
https://www.ncbi.nlm.nih.gov/pubmed/34154741
http://dx.doi.org/10.1016/j.ihj.2021.04.008
_version_ 1783731145598304256
author Kumar, Dilip
Mukherjee, Sanjeev S.
Chakraborty, Rabin
Roy, Rana Rathod
Pandey, Arindam
Patra, Soumya
Dey, Somnath
author_facet Kumar, Dilip
Mukherjee, Sanjeev S.
Chakraborty, Rabin
Roy, Rana Rathod
Pandey, Arindam
Patra, Soumya
Dey, Somnath
author_sort Kumar, Dilip
collection PubMed
description There is mounting evidence which suggests the involvement of gut microbiota dysbiosis in the pathogenesis of various cardiovascular diseases (CVD) and associated risk states such as hypertension, type 2 diabetes, obesity and dyslipidaemia, atherosclerosis, heart failure and atrial fibrillation. The current review comprehensively summarizes the various pathogenetic mechanisms of dysbiosis in these conditions and discusses the key therapeutic implications. Further deeper understanding of the pathogenetic links between CVD and gut microbiota dysbiosis can aid in the development of novel microbiota-based targets for the management of CVDs.
format Online
Article
Text
id pubmed-8322927
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-83229272021-07-31 The emerging role of gut microbiota in cardiovascular diseases Kumar, Dilip Mukherjee, Sanjeev S. Chakraborty, Rabin Roy, Rana Rathod Pandey, Arindam Patra, Soumya Dey, Somnath Indian Heart J Review Article There is mounting evidence which suggests the involvement of gut microbiota dysbiosis in the pathogenesis of various cardiovascular diseases (CVD) and associated risk states such as hypertension, type 2 diabetes, obesity and dyslipidaemia, atherosclerosis, heart failure and atrial fibrillation. The current review comprehensively summarizes the various pathogenetic mechanisms of dysbiosis in these conditions and discusses the key therapeutic implications. Further deeper understanding of the pathogenetic links between CVD and gut microbiota dysbiosis can aid in the development of novel microbiota-based targets for the management of CVDs. Elsevier 2021 2021-04-28 /pmc/articles/PMC8322927/ /pubmed/34154741 http://dx.doi.org/10.1016/j.ihj.2021.04.008 Text en © 2021 Cardiological Society of India. Published by Elsevier B.V. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Review Article
Kumar, Dilip
Mukherjee, Sanjeev S.
Chakraborty, Rabin
Roy, Rana Rathod
Pandey, Arindam
Patra, Soumya
Dey, Somnath
The emerging role of gut microbiota in cardiovascular diseases
title The emerging role of gut microbiota in cardiovascular diseases
title_full The emerging role of gut microbiota in cardiovascular diseases
title_fullStr The emerging role of gut microbiota in cardiovascular diseases
title_full_unstemmed The emerging role of gut microbiota in cardiovascular diseases
title_short The emerging role of gut microbiota in cardiovascular diseases
title_sort emerging role of gut microbiota in cardiovascular diseases
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8322927/
https://www.ncbi.nlm.nih.gov/pubmed/34154741
http://dx.doi.org/10.1016/j.ihj.2021.04.008
work_keys_str_mv AT kumardilip theemergingroleofgutmicrobiotaincardiovasculardiseases
AT mukherjeesanjeevs theemergingroleofgutmicrobiotaincardiovasculardiseases
AT chakrabortyrabin theemergingroleofgutmicrobiotaincardiovasculardiseases
AT royranarathod theemergingroleofgutmicrobiotaincardiovasculardiseases
AT pandeyarindam theemergingroleofgutmicrobiotaincardiovasculardiseases
AT patrasoumya theemergingroleofgutmicrobiotaincardiovasculardiseases
AT deysomnath theemergingroleofgutmicrobiotaincardiovasculardiseases
AT kumardilip emergingroleofgutmicrobiotaincardiovasculardiseases
AT mukherjeesanjeevs emergingroleofgutmicrobiotaincardiovasculardiseases
AT chakrabortyrabin emergingroleofgutmicrobiotaincardiovasculardiseases
AT royranarathod emergingroleofgutmicrobiotaincardiovasculardiseases
AT pandeyarindam emergingroleofgutmicrobiotaincardiovasculardiseases
AT patrasoumya emergingroleofgutmicrobiotaincardiovasculardiseases
AT deysomnath emergingroleofgutmicrobiotaincardiovasculardiseases

Ejemplares similares