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The emerging role of gut microbiota in cardiovascular diseases
There is mounting evidence which suggests the involvement of gut microbiota dysbiosis in the pathogenesis of various cardiovascular diseases (CVD) and associated risk states such as hypertension, type 2 diabetes, obesity and dyslipidaemia, atherosclerosis, heart failure and atrial fibrillation. The...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8322927/ https://www.ncbi.nlm.nih.gov/pubmed/34154741 http://dx.doi.org/10.1016/j.ihj.2021.04.008 |
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author | Kumar, Dilip Mukherjee, Sanjeev S. Chakraborty, Rabin Roy, Rana Rathod Pandey, Arindam Patra, Soumya Dey, Somnath |
author_facet | Kumar, Dilip Mukherjee, Sanjeev S. Chakraborty, Rabin Roy, Rana Rathod Pandey, Arindam Patra, Soumya Dey, Somnath |
author_sort | Kumar, Dilip |
collection | PubMed |
description | There is mounting evidence which suggests the involvement of gut microbiota dysbiosis in the pathogenesis of various cardiovascular diseases (CVD) and associated risk states such as hypertension, type 2 diabetes, obesity and dyslipidaemia, atherosclerosis, heart failure and atrial fibrillation. The current review comprehensively summarizes the various pathogenetic mechanisms of dysbiosis in these conditions and discusses the key therapeutic implications. Further deeper understanding of the pathogenetic links between CVD and gut microbiota dysbiosis can aid in the development of novel microbiota-based targets for the management of CVDs. |
format | Online Article Text |
id | pubmed-8322927 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-83229272021-07-31 The emerging role of gut microbiota in cardiovascular diseases Kumar, Dilip Mukherjee, Sanjeev S. Chakraborty, Rabin Roy, Rana Rathod Pandey, Arindam Patra, Soumya Dey, Somnath Indian Heart J Review Article There is mounting evidence which suggests the involvement of gut microbiota dysbiosis in the pathogenesis of various cardiovascular diseases (CVD) and associated risk states such as hypertension, type 2 diabetes, obesity and dyslipidaemia, atherosclerosis, heart failure and atrial fibrillation. The current review comprehensively summarizes the various pathogenetic mechanisms of dysbiosis in these conditions and discusses the key therapeutic implications. Further deeper understanding of the pathogenetic links between CVD and gut microbiota dysbiosis can aid in the development of novel microbiota-based targets for the management of CVDs. Elsevier 2021 2021-04-28 /pmc/articles/PMC8322927/ /pubmed/34154741 http://dx.doi.org/10.1016/j.ihj.2021.04.008 Text en © 2021 Cardiological Society of India. Published by Elsevier B.V. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Review Article Kumar, Dilip Mukherjee, Sanjeev S. Chakraborty, Rabin Roy, Rana Rathod Pandey, Arindam Patra, Soumya Dey, Somnath The emerging role of gut microbiota in cardiovascular diseases |
title | The emerging role of gut microbiota in cardiovascular diseases |
title_full | The emerging role of gut microbiota in cardiovascular diseases |
title_fullStr | The emerging role of gut microbiota in cardiovascular diseases |
title_full_unstemmed | The emerging role of gut microbiota in cardiovascular diseases |
title_short | The emerging role of gut microbiota in cardiovascular diseases |
title_sort | emerging role of gut microbiota in cardiovascular diseases |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8322927/ https://www.ncbi.nlm.nih.gov/pubmed/34154741 http://dx.doi.org/10.1016/j.ihj.2021.04.008 |
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