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Proteo-Genomic Analysis Identifies Two Major Sites of Vulnerability on Ebolavirus Glycoprotein for Neutralizing Antibodies in Convalescent Human Plasma

Three clinically relevant ebolaviruses – Ebola (EBOV), Bundibugyo (BDBV), and Sudan (SUDV) viruses, are responsible for severe disease and occasional deadly outbreaks in Africa. The largest Ebola virus disease (EVD) epidemic to date in 2013-2016 in West Africa highlighted the urgent need for counter...

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Detalles Bibliográficos
Autores principales: Gilchuk, Pavlo, Guthals, Adrian, Bonissone, Stefano R., Shaw, Jared B., Ilinykh, Philipp A., Huang, Kai, Bombardi, Robin G., Liang, Jenny, Grinyo, Ariadna, Davidson, Edgar, Chen, Elaine C., Gunn, Bronwyn M., Alter, Galit, Saphire, Erica Ollmann, Doranz, Benjamin J., Bukreyev, Alexander, Zeitlin, Larry, Castellana, Natalie, Crowe, James E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8322977/
https://www.ncbi.nlm.nih.gov/pubmed/34335620
http://dx.doi.org/10.3389/fimmu.2021.706757