Cargando…

Type 2 Diabetes, Metabolic Traits, and Risk of Heart Failure: A Mendelian Randomization Study

OBJECTIVE: The aim of this study was to use Mendelian randomization (MR) techniques to estimate the causal relationships between genetic liability to type 2 diabetes (T2D), glycemic traits, and risk of heart failure (HF). RESEARCH DESIGN AND METHODS: Summary-level data were obtained from genome-wide...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mordi, Ify R., Lumbers, R. Thomas, Palmer, Colin N.A., Pearson, Ewan R., Sattar, Naveed, Holmes, Michael V., Lang, Chim C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2021
Materias:	Cardiovascular and Metabolic Risk
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8323186/ https://www.ncbi.nlm.nih.gov/pubmed/34088700 http://dx.doi.org/10.2337/dc20-2518

Ejemplares similares

Sex Differences in the Risk of Coronary Heart Disease Associated With Type 2 Diabetes: A Mendelian Randomization Analysis
por: Peters, Tricia M., et al.
Publicado: (2021)

Inflammation as a therapeutic target in heart failure with preserved ejection fraction
por: Peh, Zhen Hui, et al.
Publicado: (2023)

Targeting Metabolic Modulation and Mitochondrial Dysfunction in the Treatment of Heart Failure
por: Steggall, Abbey, et al.
Publicado: (2017)

A Biomarker-Based Score for Risk of Hospitalization for Heart Failure in Patients With Diabetes
por: Berg, David D., et al.
Publicado: (2021)

Objectively Measured Physical Activity and Its Association With Adiponectin and Other Novel Metabolic Markers: A longitudinal study in children (EarlyBird 38)
por: Metcalf, Brad S., et al.
Publicado: (2009)

Intensity of statin therapy and new hospitalizations for heart failure in patients with type 2 diabetes
por: Kishimoto, Ichiro, et al.
Publicado: (2015)

The Prognostic Significance of Diabetes and Microvascular Complications in Patients With Heart Failure With Preserved Ejection Fraction
por: Sandesara, Pratik B., et al.
Publicado: (2018)

Insulin treatment in patients with diabetes mellitus and heart failure in the era of new antidiabetic medications
por: Staszewsky, Lidia, et al.
Publicado: (2022)

Network Mendelian randomization study: exploring the causal pathway from insomnia to type 2 diabetes
por: Xiuyun, Wen, et al.
Publicado: (2022)

SGLT2 Inhibition, Choline Metabolites, and Cardiometabolic Diseases: A Mediation Mendelian Randomization Study
por: Xu, Min, et al.
Publicado: (2022)

Causal associations of insulin resistance with coronary artery disease and ischemic stroke: a Mendelian randomization analysis
por: Chen, Weiqi, et al.
Publicado: (2020)

Derivation and External Validation of a Clinical Model to Predict Heart Failure Onset in Patients With Incident Diabetes
por: Sun, Louise Y., et al.
Publicado: (2022)

Women with type 2 diabetes and coronary artery disease have a higher risk of heart failure than men, with a significant gender interaction between heart failure risk and risk factor management: a retrospective registry study
por: Fujita, Yuko, et al.
Publicado: (2022)

Impaired fasting glucose and development of chronic kidney disease in non-diabetic population: a Mendelian randomization study
por: Kim, Hyoungnae, et al.
Publicado: (2020)

The association of comorbid diabetes mellitus and symptoms of depression with all-cause mortality and cardiac rehospitalization in patients with heart failure
por: Reeves, Geri C, et al.
Publicado: (2015)

Infant Body Composition and Adipokine Concentrations in Relation to Maternal Gestational Weight Gain
por: Estampador, Angela C., et al.
Publicado: (2014)

Renal and Cardiovascular Effects of sodium–glucose cotransporter 2 (SGLT2) inhibition in combination with loop Diuretics in diabetic patients with Chronic Heart Failure (RECEDE-CHF): protocol for a randomised controlled double-blind cross-over trial
por: Mordi, Natalie A, et al.
Publicado: (2017)

Heart Rate–Corrected QT Interval Is an Independent Predictor of All-Cause and Cardiovascular Mortality in Individuals With Type 2 Diabetes: The Diabetes Heart Study
por: Cox, Amanda J., et al.
Publicado: (2014)

Heart Rate and Heart Rate Variability Changes Are Not Related to Future Cardiovascular Disease and Death in People With and Without Dysglycemia: A Downfall of Risk Markers? The Whitehall II Cohort Study
por: Hansen, Christian S., et al.
Publicado: (2021)

Influence of placental and peripheral malaria exposure in fetal life on cardiometabolic traits in adult offspring
por: Grunnet, Louise G, et al.
Publicado: (2022)

Safety of medical compression stockings in patients with diabetes mellitus or peripheral arterial disease
por: Rother, Ulrich, et al.
Publicado: (2020)

Association of Lifestyle Factors With Abdominal Subcutaneous and Visceral Adiposity: The Framingham Heart Study
por: Molenaar, Esther A., et al.
Publicado: (2009)

Changes in Risk Variables of Metabolic Syndrome Since Childhood in Pre-Diabetic and Type 2 Diabetic Subjects: The Bogalusa Heart Study
por: Nguyen, Quoc Manh, et al.
Publicado: (2008)

Microvascular disease and heart failure with reduced and preserved ejection fraction in type 2 diabetes
por: Mordi, Ify R., et al.
Publicado: (2020)

Ethnic differences in prevalence of actionable HbA1c levels in UK Biobank: implications for screening
por: Anderson, Jana J, et al.
Publicado: (2021)

Patterns of Abdominal Fat Distribution: The Framingham Heart Study
por: Pou, Karla M., et al.
Publicado: (2009)

Weight trajectories since birth, current body composition and metabolic traits in young, normal-weight Japanese women with high percentage body fat
por: Minato-Inokawa, Satomi, et al.
Publicado: (2022)

Global Coronary Heart Disease Risk Assessment of Individuals With the Metabolic Syndrome in the U.S.
por: Hoang, Khiet C., et al.
Publicado: (2008)

Genetic Risk Score Associations With Cardiovascular Disease and Mortality in the Diabetes Heart Study
por: Cox, Amanda J., et al.
Publicado: (2014)

Left Ventricular Hypertrophy in Diabetic Cardiomyopathy: A Target for Intervention
por: Mohan, Mohapradeep, et al.
Publicado: (2021)

Postprandial lipemia and the risk of coronary heart disease and stroke: the Atherosclerosis Risk in Communities (ARIC) Study
por: Kats, Dmitry, et al.
Publicado: (2017)

Beta-cell failure rather than insulin resistance is the major cause of abnormal glucose tolerance in Africans: insight from the Africans in America study
por: Ishimwe, M C Sage, et al.
Publicado: (2021)

Research into the effect Of SGLT2 inhibition on left ventricular remodelling in patients with heart failure and diabetes mellitus (REFORM) trial rationale and design
por: Singh, Jagdeep S. S., et al.
Publicado: (2016)

Serum Galectin-3 and Subsequent Risk of Coronary Heart Disease in Subjects With Childhood-Onset Type 1 Diabetes: A Cohort Study
por: Saeed, Maryam, et al.
Publicado: (2021)

Heart Rate Variability and Cardiac Autonomic Dysfunction: Prevalence, Risk Factors, and Relationship to Arterial Stiffness in the Treatment Options for Type 2 Diabetes in Adolescents and Youth (TODAY) Study
por: Shah, Amy S., et al.
Publicado: (2019)

Peripheral artery disease, lower limb revascularization, and amputation in diabetes patients with and without coronary artery disease: a cohort study from the Western Denmark Heart Registry
por: Olesen, Kevin Kris Warnakula, et al.
Publicado: (2021)

Multicenter Randomized Trial of Intermittently Scanned Continuous Glucose Monitoring Versus Self-Monitoring of Blood Glucose in Individuals With Type 2 Diabetes and Recent-Onset Acute Myocardial Infarction: Results of the LIBERATES Trial
por: Ajjan, Ramzi A., et al.
Publicado: (2023)

High-throughput multivariable Mendelian randomization analysis prioritizes apolipoprotein B as key lipid risk factor for coronary artery disease
por: Zuber, Verena, et al.
Publicado: (2020)

Low Serum Vitamin D Levels Are Associated With Increased Arterial Stiffness in Youth With Type 2 Diabetes
por: Jha, Pranati, et al.
Publicado: (2015)

Incidence and determinants of hypophosphatemia in diabetic ketoacidosis: an observational study
por: van der Vaart, Amarens, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_b9r0tuqubmiimu3f0u8bnc7cvk