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Pan-cancer analysis of m(5)C regulator genes reveals consistent epigenetic landscape changes in multiple cancers

BACKGROUND: 5-Methylcytosine (m(5)C) is a reversible modification to both DNA and various cellular RNAs. However, its roles in developing human cancers are poorly understood, including the effects of mutant m(5)C regulators and the outcomes of modified nucleobases in RNAs. METHODS: Based on The Canc...

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Detalles Bibliográficos
Autores principales: He, Yuting, Yu, Xiao, Zhang, Menggang, Guo, Wenzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8323224/
https://www.ncbi.nlm.nih.gov/pubmed/34325709
http://dx.doi.org/10.1186/s12957-021-02342-y