So many ways to naturally kill a cancer cell

Natural killer (NK) cells participate in cancer immunosurveillance and cancer immunotherapy. Live cell imaging of cancer cells targeted by NK cells, published today in BMC Biology by Zhu et al., reveals a remarkable diversity of programmed cell death pathways induced in individual cells. Pathway cho...

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Detalles Bibliográficos
Autor principal: Mitchison, Timothy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8323262/
https://www.ncbi.nlm.nih.gov/pubmed/34325682
http://dx.doi.org/10.1186/s12915-021-01092-3
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author_facet Mitchison, Timothy J.
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description Natural killer (NK) cells participate in cancer immunosurveillance and cancer immunotherapy. Live cell imaging of cancer cells targeted by NK cells, published today in BMC Biology by Zhu et al., reveals a remarkable diversity of programmed cell death pathways induced in individual cells. Pathway choice depends on the state of the target cell actin cytoskeleton and a novel death pathway, granzyme-induced necroptosis, could be of broad importance in cancer immunotherapy.
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spelling pubmed-83232622021-07-30 So many ways to naturally kill a cancer cell Mitchison, Timothy J. BMC Biol Commentary Natural killer (NK) cells participate in cancer immunosurveillance and cancer immunotherapy. Live cell imaging of cancer cells targeted by NK cells, published today in BMC Biology by Zhu et al., reveals a remarkable diversity of programmed cell death pathways induced in individual cells. Pathway choice depends on the state of the target cell actin cytoskeleton and a novel death pathway, granzyme-induced necroptosis, could be of broad importance in cancer immunotherapy. BioMed Central 2021-07-30 /pmc/articles/PMC8323262/ /pubmed/34325682 http://dx.doi.org/10.1186/s12915-021-01092-3 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Commentary
Mitchison, Timothy J.
So many ways to naturally kill a cancer cell
title So many ways to naturally kill a cancer cell
title_full So many ways to naturally kill a cancer cell
title_fullStr So many ways to naturally kill a cancer cell
title_full_unstemmed So many ways to naturally kill a cancer cell
title_short So many ways to naturally kill a cancer cell
title_sort so many ways to naturally kill a cancer cell
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8323262/
https://www.ncbi.nlm.nih.gov/pubmed/34325682
http://dx.doi.org/10.1186/s12915-021-01092-3
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