Asystolic cardiac arrest following liposomal amphotericin B infusion: anaphylaxis or compliment activation-related pseudoallergy?

Allergic reaction to liposomal amphotericin B is rare. We report a case of cardiac arrest in a 64-year-old woman following liposomal amphotericin B infusion, requiring resuscitation. We also present the results of subsequent skin prick and intradermal testing to liposomal amphotericin on the patient...

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Autores principales: Drewett, George P., Copaescu, Ana, DeLuca, Joseph, Holmes, Natasha E., Trubiano, Jason A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8323293/
https://www.ncbi.nlm.nih.gov/pubmed/34325715
http://dx.doi.org/10.1186/s13223-021-00582-x
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author Drewett, George P.
Copaescu, Ana
DeLuca, Joseph
Holmes, Natasha E.
Trubiano, Jason A.
author_facet Drewett, George P.
Copaescu, Ana
DeLuca, Joseph
Holmes, Natasha E.
Trubiano, Jason A.
author_sort Drewett, George P.
collection PubMed
description Allergic reaction to liposomal amphotericin B is rare. We report a case of cardiac arrest in a 64-year-old woman following liposomal amphotericin B infusion, requiring resuscitation. We also present the results of subsequent skin prick and intradermal testing to liposomal amphotericin on the patient and three healthy controls, highlighting the need for further research into the immunopathogenesis of this reaction.
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spelling pubmed-83232932021-07-30 Asystolic cardiac arrest following liposomal amphotericin B infusion: anaphylaxis or compliment activation-related pseudoallergy? Drewett, George P. Copaescu, Ana DeLuca, Joseph Holmes, Natasha E. Trubiano, Jason A. Allergy Asthma Clin Immunol Case Report Allergic reaction to liposomal amphotericin B is rare. We report a case of cardiac arrest in a 64-year-old woman following liposomal amphotericin B infusion, requiring resuscitation. We also present the results of subsequent skin prick and intradermal testing to liposomal amphotericin on the patient and three healthy controls, highlighting the need for further research into the immunopathogenesis of this reaction. BioMed Central 2021-07-29 /pmc/articles/PMC8323293/ /pubmed/34325715 http://dx.doi.org/10.1186/s13223-021-00582-x Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Case Report
Drewett, George P.
Copaescu, Ana
DeLuca, Joseph
Holmes, Natasha E.
Trubiano, Jason A.
Asystolic cardiac arrest following liposomal amphotericin B infusion: anaphylaxis or compliment activation-related pseudoallergy?
title Asystolic cardiac arrest following liposomal amphotericin B infusion: anaphylaxis or compliment activation-related pseudoallergy?
title_full Asystolic cardiac arrest following liposomal amphotericin B infusion: anaphylaxis or compliment activation-related pseudoallergy?
title_fullStr Asystolic cardiac arrest following liposomal amphotericin B infusion: anaphylaxis or compliment activation-related pseudoallergy?
title_full_unstemmed Asystolic cardiac arrest following liposomal amphotericin B infusion: anaphylaxis or compliment activation-related pseudoallergy?
title_short Asystolic cardiac arrest following liposomal amphotericin B infusion: anaphylaxis or compliment activation-related pseudoallergy?
title_sort asystolic cardiac arrest following liposomal amphotericin b infusion: anaphylaxis or compliment activation-related pseudoallergy?
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8323293/
https://www.ncbi.nlm.nih.gov/pubmed/34325715
http://dx.doi.org/10.1186/s13223-021-00582-x
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