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Interplay of Val66Met and BDNF methylation: effect on reward learning and cognitive performance in major depression

BACKGROUND: There is a growing interest in the role of brain-derived neurotrophic factor (BDNF) in major depressive disorder (MDD). BDNF potentially exhibits opposite effects in the pathways linked to anhedonia and reward learning on the one hand and cognitive performance, on the other hand. However...

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Detalles Bibliográficos
Autores principales: Bakusic, J., Vrieze, E., Ghosh, M., Pizzagalli, D. A., Bekaert, B., Claes, S., Godderis, L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8323304/
https://www.ncbi.nlm.nih.gov/pubmed/34325733
http://dx.doi.org/10.1186/s13148-021-01136-z