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Haemodialysed patient with lung cancer in the COVID-19 era: a clinical challenge

A 66-year-old man was referred to the oncological pneumology consultation due to a mass in the right upper lobe observed in a routine X-ray of the chest. The CT scan confirmed a mass in the same location. The biopsy revealed a lung adenocarcinoma. It was decided to start chemotherapy adapted to kidn...

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Detalles Bibliográficos
Autores principales: Carvalho, Tomás de Paiva, Trinca, Francisco, Cardoso, Teresa, Dinis, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8323347/
https://www.ncbi.nlm.nih.gov/pubmed/34326113
http://dx.doi.org/10.1136/bcr-2021-243462
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author Carvalho, Tomás de Paiva
Trinca, Francisco
Cardoso, Teresa
Dinis, Rui
author_facet Carvalho, Tomás de Paiva
Trinca, Francisco
Cardoso, Teresa
Dinis, Rui
author_sort Carvalho, Tomás de Paiva
collection PubMed
description A 66-year-old man was referred to the oncological pneumology consultation due to a mass in the right upper lobe observed in a routine X-ray of the chest. The CT scan confirmed a mass in the same location. The biopsy revealed a lung adenocarcinoma. It was decided to start chemotherapy adapted to kidney function. In April 2020, the patient contracted SARS-CoV-2 infection and developed bilateral pneumonia with partial respiratory failure. He was transferred to the intensive care unit, where he had a positive evolution. In the next 5 months, there was a clinical improvement; however, the CT scan of the chest showed disease progression. After a new multidisciplinary approach, it was decided to start a second line with atezolizumab. After four cycles of atezolizumab, there was a clear clinical improvement, and a reduction by more than 50% in the tumour size, without significant adverse effects.
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spelling pubmed-83233472021-08-19 Haemodialysed patient with lung cancer in the COVID-19 era: a clinical challenge Carvalho, Tomás de Paiva Trinca, Francisco Cardoso, Teresa Dinis, Rui BMJ Case Rep Case Report A 66-year-old man was referred to the oncological pneumology consultation due to a mass in the right upper lobe observed in a routine X-ray of the chest. The CT scan confirmed a mass in the same location. The biopsy revealed a lung adenocarcinoma. It was decided to start chemotherapy adapted to kidney function. In April 2020, the patient contracted SARS-CoV-2 infection and developed bilateral pneumonia with partial respiratory failure. He was transferred to the intensive care unit, where he had a positive evolution. In the next 5 months, there was a clinical improvement; however, the CT scan of the chest showed disease progression. After a new multidisciplinary approach, it was decided to start a second line with atezolizumab. After four cycles of atezolizumab, there was a clear clinical improvement, and a reduction by more than 50% in the tumour size, without significant adverse effects. BMJ Publishing Group 2021-07-29 /pmc/articles/PMC8323347/ /pubmed/34326113 http://dx.doi.org/10.1136/bcr-2021-243462 Text en © BMJ Publishing Group Limited 2021. No commercial re-use. See rights and permissions. Published by BMJ. https://bmj.com/coronavirus/usageThis article is made freely available for use in accordance with BMJ’s website terms and conditions for the duration of the covid-19 pandemic or until otherwise determined by BMJ. You may use, download and print the article for any lawful, non-commercial purpose (including text and data mining) provided that all copyright notices and trade marks are retained.
spellingShingle Case Report
Carvalho, Tomás de Paiva
Trinca, Francisco
Cardoso, Teresa
Dinis, Rui
Haemodialysed patient with lung cancer in the COVID-19 era: a clinical challenge
title Haemodialysed patient with lung cancer in the COVID-19 era: a clinical challenge
title_full Haemodialysed patient with lung cancer in the COVID-19 era: a clinical challenge
title_fullStr Haemodialysed patient with lung cancer in the COVID-19 era: a clinical challenge
title_full_unstemmed Haemodialysed patient with lung cancer in the COVID-19 era: a clinical challenge
title_short Haemodialysed patient with lung cancer in the COVID-19 era: a clinical challenge
title_sort haemodialysed patient with lung cancer in the covid-19 era: a clinical challenge
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8323347/
https://www.ncbi.nlm.nih.gov/pubmed/34326113
http://dx.doi.org/10.1136/bcr-2021-243462
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