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Overexpression of CD200 is a stem cell-specific mechanism of immune evasion in AML

BACKGROUND: Acute myeloid leukemia (AML) stem cells (LSCs) are capable of surviving current standard chemotherapy and are the likely source of deadly, relapsed disease. While stem cell transplant serves as proof-of-principle that AML LSCs can be eliminated by the immune system, the translation of ex...

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Detalles Bibliográficos
Autores principales:	Herbrich, Shelley, Baran, Natalia, Cai, Tianyu, Weng, Connie, Aitken, Marisa J L, Post, Sean M, Henderson, Jared, Shi, Chunhua, Havranek, Ondrej, Richard-Carpentier, Guillame, Sauvageau, Guy, Baggerly, Keith, Al-Atrash, Gheath, Davis, R Eric, Daver, Naval, Zha, Dongxing, Konopleva, Marina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2021
Materias:	Basic Tumor Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8323398/ https://www.ncbi.nlm.nih.gov/pubmed/34326171 http://dx.doi.org/10.1136/jitc-2021-002968

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