Vaccine breakthrough infection and onward transmission of SARS-CoV-2 Beta (B.1.351) variant, Bavaria, Germany, February to March 2021

A breakthrough infection occurred in a fully Comirnaty (BNT162b2) vaccinated healthcare worker with high levels of neutralising antibodies with the SARS-CoV-2 B.1.351 (Beta) variant in February 2021. The infection was subsequently transmitted to their unvaccinated spouse. Sequencing revealed an iden...

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Autores principales: Kroidl, Inge, Mecklenburg, Ingo, Schneiderat, Peter, Müller, Katharina, Girl, Philipp, Wölfel, Roman, Sing, Andreas, Dangel, Alexandra, Wieser, Andreas, Hoelscher, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Centre for Disease Prevention and Control (ECDC) 2021
Materias:
Rapid Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8323454/
https://www.ncbi.nlm.nih.gov/pubmed/34328074
http://dx.doi.org/10.2807/1560-7917.ES.2021.26.30.2100673
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author Kroidl, Inge
Mecklenburg, Ingo
Schneiderat, Peter
Müller, Katharina
Girl, Philipp
Wölfel, Roman
Sing, Andreas
Dangel, Alexandra
Wieser, Andreas
Hoelscher, Michael
author_facet Kroidl, Inge
Mecklenburg, Ingo
Schneiderat, Peter
Müller, Katharina
Girl, Philipp
Wölfel, Roman
Sing, Andreas
Dangel, Alexandra
Wieser, Andreas
Hoelscher, Michael
author_sort Kroidl, Inge
collection PubMed
description A breakthrough infection occurred in a fully Comirnaty (BNT162b2) vaccinated healthcare worker with high levels of neutralising antibodies with the SARS-CoV-2 B.1.351 (Beta) variant in February 2021. The infection was subsequently transmitted to their unvaccinated spouse. Sequencing revealed an identical virus in both spouses, with a match of all nine single nucleotide polymorphisms typical for B.1.351. To the best of our knowledge, no transmission of any variant of SARS-CoV-2 from a fully vaccinated person has been described before.
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spelling pubmed-83234542021-08-11 Vaccine breakthrough infection and onward transmission of SARS-CoV-2 Beta (B.1.351) variant, Bavaria, Germany, February to March 2021 Kroidl, Inge Mecklenburg, Ingo Schneiderat, Peter Müller, Katharina Girl, Philipp Wölfel, Roman Sing, Andreas Dangel, Alexandra Wieser, Andreas Hoelscher, Michael Euro Surveill Rapid Communication A breakthrough infection occurred in a fully Comirnaty (BNT162b2) vaccinated healthcare worker with high levels of neutralising antibodies with the SARS-CoV-2 B.1.351 (Beta) variant in February 2021. The infection was subsequently transmitted to their unvaccinated spouse. Sequencing revealed an identical virus in both spouses, with a match of all nine single nucleotide polymorphisms typical for B.1.351. To the best of our knowledge, no transmission of any variant of SARS-CoV-2 from a fully vaccinated person has been described before. European Centre for Disease Prevention and Control (ECDC) 2021-07-29 /pmc/articles/PMC8323454/ /pubmed/34328074 http://dx.doi.org/10.2807/1560-7917.ES.2021.26.30.2100673 Text en This article is copyright of the authors or their affiliated institutions, 2021. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution (CC BY 4.0) Licence. You may share and adapt the material, but must give appropriate credit to the source, provide a link to the licence, and indicate if changes were made.
spellingShingle Rapid Communication
Kroidl, Inge
Mecklenburg, Ingo
Schneiderat, Peter
Müller, Katharina
Girl, Philipp
Wölfel, Roman
Sing, Andreas
Dangel, Alexandra
Wieser, Andreas
Hoelscher, Michael
Vaccine breakthrough infection and onward transmission of SARS-CoV-2 Beta (B.1.351) variant, Bavaria, Germany, February to March 2021
title Vaccine breakthrough infection and onward transmission of SARS-CoV-2 Beta (B.1.351) variant, Bavaria, Germany, February to March 2021
title_full Vaccine breakthrough infection and onward transmission of SARS-CoV-2 Beta (B.1.351) variant, Bavaria, Germany, February to March 2021
title_fullStr Vaccine breakthrough infection and onward transmission of SARS-CoV-2 Beta (B.1.351) variant, Bavaria, Germany, February to March 2021
title_full_unstemmed Vaccine breakthrough infection and onward transmission of SARS-CoV-2 Beta (B.1.351) variant, Bavaria, Germany, February to March 2021
title_short Vaccine breakthrough infection and onward transmission of SARS-CoV-2 Beta (B.1.351) variant, Bavaria, Germany, February to March 2021
title_sort vaccine breakthrough infection and onward transmission of sars-cov-2 beta (b.1.351) variant, bavaria, germany, february to march 2021
topic Rapid Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8323454/
https://www.ncbi.nlm.nih.gov/pubmed/34328074
http://dx.doi.org/10.2807/1560-7917.ES.2021.26.30.2100673
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