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Efficacy and Tolerability of First Line Arsenic Trioxide in Combination With All-Trans Retinoic Acid in Patients With Acute Promyelocytic Leukemia: Real Life Experience
Acute promyelocytic leukemia is a variant of acute myeloid leukemia characterized by t(15;17) and PML/RAR alfa fusion gene. The discovery of the molecular pathogenesis has led to entitle all-trans retinoic acid (ATRA) as the first targeted therapy for acute leukemia. It is usually associated to anth...
Autores principales: | Autore, Francesco, Chiusolo, Patrizia, Sorà, Federica, Giammarco, Sabrina, Laurenti, Luca, Innocenti, Idanna, Metafuni, Elisabetta, Piccirillo, Nicola, Pagano, Livio, Sica, Simona |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8323479/ https://www.ncbi.nlm.nih.gov/pubmed/34336637 http://dx.doi.org/10.3389/fonc.2021.614721 |
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