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Doublecortin-Like Kinase 1 (DCLK1) Is a Novel NOTCH Pathway Signaling Regulator in Head and Neck Squamous Cell Carcinoma
Despite recent advancements, the 5 year survival of head and neck squamous cell carcinoma (HNSCC) hovers at 60%. DCLK1 has been shown to regulate epithelial-to-mesenchymal transition as well as serving as a cancer stem cell marker in colon, pancreatic and renal cancer. Although it was reported that...
Autores principales: | Broner, Esther C., Trujillo, Jonathan A., Korzinkin, Michael, Subbannayya, Tejaswini, Agrawal, Nishant, Ozerov, Ivan V., Zhavoronkov, Alex, Rooper, Lisa, Kotlov, Nikita, Shen, Le, Pearson, Alexander T., Rosenberg, Ari J., Savage, Peter A., Mishra, Vasudha, Chatterjee, Aditi, Sidransky, David, Izumchenko, Evgeny |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8323482/ https://www.ncbi.nlm.nih.gov/pubmed/34336664 http://dx.doi.org/10.3389/fonc.2021.677051 |
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