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Mathematical model of COVID-19 in Nigeria with optimal control

The novel Coronavirus Disease 2019 (COVID-19) is a highly infectious disease caused by a new strain of severe acute respiratory syndrome of coronavirus 2 (SARS-CoV-2). In this work, we proposed a mathematical model of COVID-19. We carried out the qualitative analysis along with an epidemic indicator...

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Detalles Bibliográficos
Autores principales: Abioye, Adesoye Idowu, Peter, Olumuyiwa James, Ogunseye, Hammed Abiodun, Oguntolu, Festus Abiodun, Oshinubi, Kayode, Ibrahim, Abdullahi Adinoyi, Khan, Ilyas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). Published by Elsevier B.V. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8323584/
https://www.ncbi.nlm.nih.gov/pubmed/34345579
http://dx.doi.org/10.1016/j.rinp.2021.104598
Descripción
Sumario:The novel Coronavirus Disease 2019 (COVID-19) is a highly infectious disease caused by a new strain of severe acute respiratory syndrome of coronavirus 2 (SARS-CoV-2). In this work, we proposed a mathematical model of COVID-19. We carried out the qualitative analysis along with an epidemic indicator which is the basic reproduction number ([Formula: see text]) of this model, stability analysis of COVID-19 free equilibrium (CFE) and Endemic equilibrium (EE) using Lyaponuv function are considered. We extended the basic model into optimal control system by incorporating three control strategies. These are; use of face-mask and hand sanitizer along with social distancing; treatment of COVID-19 patients and active screening with testing and the third control is prevention against recurrence and reinfection of humans who have recovered from COVID-19. Daily data given by Nigeria Center for Disease Control (NCDC) in Nigeria is used for simulation of the proposed COVID-19 model to see the effects of the control measures. The biological interpretation of this findings is that, COVID-19 can be effectively managed or eliminated in Nigeria if the control measures implemented are capable of taking or sustaining the basic reproductive number [Formula: see text] to a value below unity. If the three control strategies are well managed by the government namely; NCDC, Presidential Task Force (PTF) and Federal Ministry of Health (FMOH) or policymakers, then COVID-19 in Nigeria will be eradicated.