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Mathematical model of COVID-19 in Nigeria with optimal control
The novel Coronavirus Disease 2019 (COVID-19) is a highly infectious disease caused by a new strain of severe acute respiratory syndrome of coronavirus 2 (SARS-CoV-2). In this work, we proposed a mathematical model of COVID-19. We carried out the qualitative analysis along with an epidemic indicator...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Author(s). Published by Elsevier B.V.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8323584/ https://www.ncbi.nlm.nih.gov/pubmed/34345579 http://dx.doi.org/10.1016/j.rinp.2021.104598 |
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author | Abioye, Adesoye Idowu Peter, Olumuyiwa James Ogunseye, Hammed Abiodun Oguntolu, Festus Abiodun Oshinubi, Kayode Ibrahim, Abdullahi Adinoyi Khan, Ilyas |
author_facet | Abioye, Adesoye Idowu Peter, Olumuyiwa James Ogunseye, Hammed Abiodun Oguntolu, Festus Abiodun Oshinubi, Kayode Ibrahim, Abdullahi Adinoyi Khan, Ilyas |
author_sort | Abioye, Adesoye Idowu |
collection | PubMed |
description | The novel Coronavirus Disease 2019 (COVID-19) is a highly infectious disease caused by a new strain of severe acute respiratory syndrome of coronavirus 2 (SARS-CoV-2). In this work, we proposed a mathematical model of COVID-19. We carried out the qualitative analysis along with an epidemic indicator which is the basic reproduction number ([Formula: see text]) of this model, stability analysis of COVID-19 free equilibrium (CFE) and Endemic equilibrium (EE) using Lyaponuv function are considered. We extended the basic model into optimal control system by incorporating three control strategies. These are; use of face-mask and hand sanitizer along with social distancing; treatment of COVID-19 patients and active screening with testing and the third control is prevention against recurrence and reinfection of humans who have recovered from COVID-19. Daily data given by Nigeria Center for Disease Control (NCDC) in Nigeria is used for simulation of the proposed COVID-19 model to see the effects of the control measures. The biological interpretation of this findings is that, COVID-19 can be effectively managed or eliminated in Nigeria if the control measures implemented are capable of taking or sustaining the basic reproductive number [Formula: see text] to a value below unity. If the three control strategies are well managed by the government namely; NCDC, Presidential Task Force (PTF) and Federal Ministry of Health (FMOH) or policymakers, then COVID-19 in Nigeria will be eradicated. |
format | Online Article Text |
id | pubmed-8323584 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | The Author(s). Published by Elsevier B.V. |
record_format | MEDLINE/PubMed |
spelling | pubmed-83235842021-07-30 Mathematical model of COVID-19 in Nigeria with optimal control Abioye, Adesoye Idowu Peter, Olumuyiwa James Ogunseye, Hammed Abiodun Oguntolu, Festus Abiodun Oshinubi, Kayode Ibrahim, Abdullahi Adinoyi Khan, Ilyas Results Phys Article The novel Coronavirus Disease 2019 (COVID-19) is a highly infectious disease caused by a new strain of severe acute respiratory syndrome of coronavirus 2 (SARS-CoV-2). In this work, we proposed a mathematical model of COVID-19. We carried out the qualitative analysis along with an epidemic indicator which is the basic reproduction number ([Formula: see text]) of this model, stability analysis of COVID-19 free equilibrium (CFE) and Endemic equilibrium (EE) using Lyaponuv function are considered. We extended the basic model into optimal control system by incorporating three control strategies. These are; use of face-mask and hand sanitizer along with social distancing; treatment of COVID-19 patients and active screening with testing and the third control is prevention against recurrence and reinfection of humans who have recovered from COVID-19. Daily data given by Nigeria Center for Disease Control (NCDC) in Nigeria is used for simulation of the proposed COVID-19 model to see the effects of the control measures. The biological interpretation of this findings is that, COVID-19 can be effectively managed or eliminated in Nigeria if the control measures implemented are capable of taking or sustaining the basic reproductive number [Formula: see text] to a value below unity. If the three control strategies are well managed by the government namely; NCDC, Presidential Task Force (PTF) and Federal Ministry of Health (FMOH) or policymakers, then COVID-19 in Nigeria will be eradicated. The Author(s). Published by Elsevier B.V. 2021-09 2021-07-30 /pmc/articles/PMC8323584/ /pubmed/34345579 http://dx.doi.org/10.1016/j.rinp.2021.104598 Text en © 2021 The Author(s) Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Article Abioye, Adesoye Idowu Peter, Olumuyiwa James Ogunseye, Hammed Abiodun Oguntolu, Festus Abiodun Oshinubi, Kayode Ibrahim, Abdullahi Adinoyi Khan, Ilyas Mathematical model of COVID-19 in Nigeria with optimal control |
title | Mathematical model of COVID-19 in Nigeria with optimal control |
title_full | Mathematical model of COVID-19 in Nigeria with optimal control |
title_fullStr | Mathematical model of COVID-19 in Nigeria with optimal control |
title_full_unstemmed | Mathematical model of COVID-19 in Nigeria with optimal control |
title_short | Mathematical model of COVID-19 in Nigeria with optimal control |
title_sort | mathematical model of covid-19 in nigeria with optimal control |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8323584/ https://www.ncbi.nlm.nih.gov/pubmed/34345579 http://dx.doi.org/10.1016/j.rinp.2021.104598 |
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