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Mathematical model of COVID-19 in Nigeria with optimal control

The novel Coronavirus Disease 2019 (COVID-19) is a highly infectious disease caused by a new strain of severe acute respiratory syndrome of coronavirus 2 (SARS-CoV-2). In this work, we proposed a mathematical model of COVID-19. We carried out the qualitative analysis along with an epidemic indicator...

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Autores principales: Abioye, Adesoye Idowu, Peter, Olumuyiwa James, Ogunseye, Hammed Abiodun, Oguntolu, Festus Abiodun, Oshinubi, Kayode, Ibrahim, Abdullahi Adinoyi, Khan, Ilyas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). Published by Elsevier B.V. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8323584/
https://www.ncbi.nlm.nih.gov/pubmed/34345579
http://dx.doi.org/10.1016/j.rinp.2021.104598
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author Abioye, Adesoye Idowu
Peter, Olumuyiwa James
Ogunseye, Hammed Abiodun
Oguntolu, Festus Abiodun
Oshinubi, Kayode
Ibrahim, Abdullahi Adinoyi
Khan, Ilyas
author_facet Abioye, Adesoye Idowu
Peter, Olumuyiwa James
Ogunseye, Hammed Abiodun
Oguntolu, Festus Abiodun
Oshinubi, Kayode
Ibrahim, Abdullahi Adinoyi
Khan, Ilyas
author_sort Abioye, Adesoye Idowu
collection PubMed
description The novel Coronavirus Disease 2019 (COVID-19) is a highly infectious disease caused by a new strain of severe acute respiratory syndrome of coronavirus 2 (SARS-CoV-2). In this work, we proposed a mathematical model of COVID-19. We carried out the qualitative analysis along with an epidemic indicator which is the basic reproduction number ([Formula: see text]) of this model, stability analysis of COVID-19 free equilibrium (CFE) and Endemic equilibrium (EE) using Lyaponuv function are considered. We extended the basic model into optimal control system by incorporating three control strategies. These are; use of face-mask and hand sanitizer along with social distancing; treatment of COVID-19 patients and active screening with testing and the third control is prevention against recurrence and reinfection of humans who have recovered from COVID-19. Daily data given by Nigeria Center for Disease Control (NCDC) in Nigeria is used for simulation of the proposed COVID-19 model to see the effects of the control measures. The biological interpretation of this findings is that, COVID-19 can be effectively managed or eliminated in Nigeria if the control measures implemented are capable of taking or sustaining the basic reproductive number [Formula: see text] to a value below unity. If the three control strategies are well managed by the government namely; NCDC, Presidential Task Force (PTF) and Federal Ministry of Health (FMOH) or policymakers, then COVID-19 in Nigeria will be eradicated.
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spelling pubmed-83235842021-07-30 Mathematical model of COVID-19 in Nigeria with optimal control Abioye, Adesoye Idowu Peter, Olumuyiwa James Ogunseye, Hammed Abiodun Oguntolu, Festus Abiodun Oshinubi, Kayode Ibrahim, Abdullahi Adinoyi Khan, Ilyas Results Phys Article The novel Coronavirus Disease 2019 (COVID-19) is a highly infectious disease caused by a new strain of severe acute respiratory syndrome of coronavirus 2 (SARS-CoV-2). In this work, we proposed a mathematical model of COVID-19. We carried out the qualitative analysis along with an epidemic indicator which is the basic reproduction number ([Formula: see text]) of this model, stability analysis of COVID-19 free equilibrium (CFE) and Endemic equilibrium (EE) using Lyaponuv function are considered. We extended the basic model into optimal control system by incorporating three control strategies. These are; use of face-mask and hand sanitizer along with social distancing; treatment of COVID-19 patients and active screening with testing and the third control is prevention against recurrence and reinfection of humans who have recovered from COVID-19. Daily data given by Nigeria Center for Disease Control (NCDC) in Nigeria is used for simulation of the proposed COVID-19 model to see the effects of the control measures. The biological interpretation of this findings is that, COVID-19 can be effectively managed or eliminated in Nigeria if the control measures implemented are capable of taking or sustaining the basic reproductive number [Formula: see text] to a value below unity. If the three control strategies are well managed by the government namely; NCDC, Presidential Task Force (PTF) and Federal Ministry of Health (FMOH) or policymakers, then COVID-19 in Nigeria will be eradicated. The Author(s). Published by Elsevier B.V. 2021-09 2021-07-30 /pmc/articles/PMC8323584/ /pubmed/34345579 http://dx.doi.org/10.1016/j.rinp.2021.104598 Text en © 2021 The Author(s) Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Abioye, Adesoye Idowu
Peter, Olumuyiwa James
Ogunseye, Hammed Abiodun
Oguntolu, Festus Abiodun
Oshinubi, Kayode
Ibrahim, Abdullahi Adinoyi
Khan, Ilyas
Mathematical model of COVID-19 in Nigeria with optimal control
title Mathematical model of COVID-19 in Nigeria with optimal control
title_full Mathematical model of COVID-19 in Nigeria with optimal control
title_fullStr Mathematical model of COVID-19 in Nigeria with optimal control
title_full_unstemmed Mathematical model of COVID-19 in Nigeria with optimal control
title_short Mathematical model of COVID-19 in Nigeria with optimal control
title_sort mathematical model of covid-19 in nigeria with optimal control
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8323584/
https://www.ncbi.nlm.nih.gov/pubmed/34345579
http://dx.doi.org/10.1016/j.rinp.2021.104598
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