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Lipid Profile in Infant

INTRODUCTION: Alteration in lipid parameters at birth has a strong association with the development of cardiovascular disease in later life. MATERIAL AND METHODS: Sixty-one infants below the age of 6 months underwent evaluation of lipid parameters. The infants studied were categorized into two group...

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Autores principales: Kumar, Ashok, Pandit, Kaushik, Chatterjee, Purushottam, Mukhopadhyay, Pradip, Ghosh, Sujoy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8323631/
https://www.ncbi.nlm.nih.gov/pubmed/34386389
http://dx.doi.org/10.4103/ijem.IJEM_396_20
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author Kumar, Ashok
Pandit, Kaushik
Chatterjee, Purushottam
Mukhopadhyay, Pradip
Ghosh, Sujoy
author_facet Kumar, Ashok
Pandit, Kaushik
Chatterjee, Purushottam
Mukhopadhyay, Pradip
Ghosh, Sujoy
author_sort Kumar, Ashok
collection PubMed
description INTRODUCTION: Alteration in lipid parameters at birth has a strong association with the development of cardiovascular disease in later life. MATERIAL AND METHODS: Sixty-one infants below the age of 6 months underwent evaluation of lipid parameters. The infants studied were categorized into two groups of ≤4 and >4 weeks of age, wherein their lipid parameters were compared. RESULTS: The normal distribution of lipid parameters of infants <6 months was generated. The mean total cholesterol, triglyceride, HDL-cholesterol, LDL-cholesterol was 126.2 ± 26.5, 149.1 ± 48.6, 40.7 ± 14.6, and 69.4 ± 19.4 mg/dl, respectively. The total cholesterol and LDL-cholesterol measured in ≤4 and >4 weeks of age groups were statistically not different (total cholesterol 125.0 ± 30.1 mg/dl vs 127.4 ± 23.4 mg/dl, P = 0.727, and LDL-cholesterol 66.0 ± 19.2 mg/dl vs 75.4 ± 21.2 mg/dl, P = 0.780). However, the HDL-cholesterol and triglycerides measured at ≤4 weeks versus >4 weeks age groups were statistically different (HDL-cholesterol 44.9 ± 17.2 mg/dl vs 36.9 ± 10.8 mg/dl, P = 0.031, and triglyceride 147.4 ± 60.2 mg/dl vs 186.5 ± 75.7 mg/dl, P = 0.030). CONCLUSION: The mean lipid parameters were significantly more atherogenic compared to the Western population. Triglyceride levels and HDL-cholesterol levels change significantly after 4 weeks of age compared to that observed before 4 weeks of age.
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spelling pubmed-83236312021-08-11 Lipid Profile in Infant Kumar, Ashok Pandit, Kaushik Chatterjee, Purushottam Mukhopadhyay, Pradip Ghosh, Sujoy Indian J Endocrinol Metab Original Article INTRODUCTION: Alteration in lipid parameters at birth has a strong association with the development of cardiovascular disease in later life. MATERIAL AND METHODS: Sixty-one infants below the age of 6 months underwent evaluation of lipid parameters. The infants studied were categorized into two groups of ≤4 and >4 weeks of age, wherein their lipid parameters were compared. RESULTS: The normal distribution of lipid parameters of infants <6 months was generated. The mean total cholesterol, triglyceride, HDL-cholesterol, LDL-cholesterol was 126.2 ± 26.5, 149.1 ± 48.6, 40.7 ± 14.6, and 69.4 ± 19.4 mg/dl, respectively. The total cholesterol and LDL-cholesterol measured in ≤4 and >4 weeks of age groups were statistically not different (total cholesterol 125.0 ± 30.1 mg/dl vs 127.4 ± 23.4 mg/dl, P = 0.727, and LDL-cholesterol 66.0 ± 19.2 mg/dl vs 75.4 ± 21.2 mg/dl, P = 0.780). However, the HDL-cholesterol and triglycerides measured at ≤4 weeks versus >4 weeks age groups were statistically different (HDL-cholesterol 44.9 ± 17.2 mg/dl vs 36.9 ± 10.8 mg/dl, P = 0.031, and triglyceride 147.4 ± 60.2 mg/dl vs 186.5 ± 75.7 mg/dl, P = 0.030). CONCLUSION: The mean lipid parameters were significantly more atherogenic compared to the Western population. Triglyceride levels and HDL-cholesterol levels change significantly after 4 weeks of age compared to that observed before 4 weeks of age. Wolters Kluwer - Medknow 2021 2021-07-21 /pmc/articles/PMC8323631/ /pubmed/34386389 http://dx.doi.org/10.4103/ijem.IJEM_396_20 Text en Copyright: © 2021 Indian Journal of Endocrinology and Metabolism https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Kumar, Ashok
Pandit, Kaushik
Chatterjee, Purushottam
Mukhopadhyay, Pradip
Ghosh, Sujoy
Lipid Profile in Infant
title Lipid Profile in Infant
title_full Lipid Profile in Infant
title_fullStr Lipid Profile in Infant
title_full_unstemmed Lipid Profile in Infant
title_short Lipid Profile in Infant
title_sort lipid profile in infant
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8323631/
https://www.ncbi.nlm.nih.gov/pubmed/34386389
http://dx.doi.org/10.4103/ijem.IJEM_396_20
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