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Lipid Profile in Infant
INTRODUCTION: Alteration in lipid parameters at birth has a strong association with the development of cardiovascular disease in later life. MATERIAL AND METHODS: Sixty-one infants below the age of 6 months underwent evaluation of lipid parameters. The infants studied were categorized into two group...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8323631/ https://www.ncbi.nlm.nih.gov/pubmed/34386389 http://dx.doi.org/10.4103/ijem.IJEM_396_20 |
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author | Kumar, Ashok Pandit, Kaushik Chatterjee, Purushottam Mukhopadhyay, Pradip Ghosh, Sujoy |
author_facet | Kumar, Ashok Pandit, Kaushik Chatterjee, Purushottam Mukhopadhyay, Pradip Ghosh, Sujoy |
author_sort | Kumar, Ashok |
collection | PubMed |
description | INTRODUCTION: Alteration in lipid parameters at birth has a strong association with the development of cardiovascular disease in later life. MATERIAL AND METHODS: Sixty-one infants below the age of 6 months underwent evaluation of lipid parameters. The infants studied were categorized into two groups of ≤4 and >4 weeks of age, wherein their lipid parameters were compared. RESULTS: The normal distribution of lipid parameters of infants <6 months was generated. The mean total cholesterol, triglyceride, HDL-cholesterol, LDL-cholesterol was 126.2 ± 26.5, 149.1 ± 48.6, 40.7 ± 14.6, and 69.4 ± 19.4 mg/dl, respectively. The total cholesterol and LDL-cholesterol measured in ≤4 and >4 weeks of age groups were statistically not different (total cholesterol 125.0 ± 30.1 mg/dl vs 127.4 ± 23.4 mg/dl, P = 0.727, and LDL-cholesterol 66.0 ± 19.2 mg/dl vs 75.4 ± 21.2 mg/dl, P = 0.780). However, the HDL-cholesterol and triglycerides measured at ≤4 weeks versus >4 weeks age groups were statistically different (HDL-cholesterol 44.9 ± 17.2 mg/dl vs 36.9 ± 10.8 mg/dl, P = 0.031, and triglyceride 147.4 ± 60.2 mg/dl vs 186.5 ± 75.7 mg/dl, P = 0.030). CONCLUSION: The mean lipid parameters were significantly more atherogenic compared to the Western population. Triglyceride levels and HDL-cholesterol levels change significantly after 4 weeks of age compared to that observed before 4 weeks of age. |
format | Online Article Text |
id | pubmed-8323631 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Wolters Kluwer - Medknow |
record_format | MEDLINE/PubMed |
spelling | pubmed-83236312021-08-11 Lipid Profile in Infant Kumar, Ashok Pandit, Kaushik Chatterjee, Purushottam Mukhopadhyay, Pradip Ghosh, Sujoy Indian J Endocrinol Metab Original Article INTRODUCTION: Alteration in lipid parameters at birth has a strong association with the development of cardiovascular disease in later life. MATERIAL AND METHODS: Sixty-one infants below the age of 6 months underwent evaluation of lipid parameters. The infants studied were categorized into two groups of ≤4 and >4 weeks of age, wherein their lipid parameters were compared. RESULTS: The normal distribution of lipid parameters of infants <6 months was generated. The mean total cholesterol, triglyceride, HDL-cholesterol, LDL-cholesterol was 126.2 ± 26.5, 149.1 ± 48.6, 40.7 ± 14.6, and 69.4 ± 19.4 mg/dl, respectively. The total cholesterol and LDL-cholesterol measured in ≤4 and >4 weeks of age groups were statistically not different (total cholesterol 125.0 ± 30.1 mg/dl vs 127.4 ± 23.4 mg/dl, P = 0.727, and LDL-cholesterol 66.0 ± 19.2 mg/dl vs 75.4 ± 21.2 mg/dl, P = 0.780). However, the HDL-cholesterol and triglycerides measured at ≤4 weeks versus >4 weeks age groups were statistically different (HDL-cholesterol 44.9 ± 17.2 mg/dl vs 36.9 ± 10.8 mg/dl, P = 0.031, and triglyceride 147.4 ± 60.2 mg/dl vs 186.5 ± 75.7 mg/dl, P = 0.030). CONCLUSION: The mean lipid parameters were significantly more atherogenic compared to the Western population. Triglyceride levels and HDL-cholesterol levels change significantly after 4 weeks of age compared to that observed before 4 weeks of age. Wolters Kluwer - Medknow 2021 2021-07-21 /pmc/articles/PMC8323631/ /pubmed/34386389 http://dx.doi.org/10.4103/ijem.IJEM_396_20 Text en Copyright: © 2021 Indian Journal of Endocrinology and Metabolism https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Original Article Kumar, Ashok Pandit, Kaushik Chatterjee, Purushottam Mukhopadhyay, Pradip Ghosh, Sujoy Lipid Profile in Infant |
title | Lipid Profile in Infant |
title_full | Lipid Profile in Infant |
title_fullStr | Lipid Profile in Infant |
title_full_unstemmed | Lipid Profile in Infant |
title_short | Lipid Profile in Infant |
title_sort | lipid profile in infant |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8323631/ https://www.ncbi.nlm.nih.gov/pubmed/34386389 http://dx.doi.org/10.4103/ijem.IJEM_396_20 |
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