Revealing molecular pathways for cancer cell fitness through a genetic screen of the cancer translatome

The major cap-binding protein eukaryotic translation initiation factor 4E (eIF4E), an ancient protein required for translation of all eukaryotic genomes, is a surprising yet potent oncogenic driver. The genetic interactions that maintain the oncogenic activity of this key translation factor remain u...

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Detalles Bibliográficos
Autores principales: Kuzuoglu-Ozturk, Duygu, Hu, Zhiqiang, Rama, Martina, Devericks, Emily, Weiss, Jacob, Chiang, Gary G., Worland, Stephen T., Brenner, Steven E., Goodarzi, Hani, Gilbert, Luke A., Ruggero, Davide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8323864/
https://www.ncbi.nlm.nih.gov/pubmed/34192540
http://dx.doi.org/10.1016/j.celrep.2021.109321

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8323864/
https://www.ncbi.nlm.nih.gov/pubmed/34192540
http://dx.doi.org/10.1016/j.celrep.2021.109321

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