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Revealing molecular pathways for cancer cell fitness through a genetic screen of the cancer translatome
The major cap-binding protein eukaryotic translation initiation factor 4E (eIF4E), an ancient protein required for translation of all eukaryotic genomes, is a surprising yet potent oncogenic driver. The genetic interactions that maintain the oncogenic activity of this key translation factor remain u...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8323864/ https://www.ncbi.nlm.nih.gov/pubmed/34192540 http://dx.doi.org/10.1016/j.celrep.2021.109321 |