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Implications of Lifestyle Factors and Polygenic Risk Score for Absolute Risk Prediction of Colorectal Neoplasm and Risk-Adapted Screening

Background: Estimation of absolute risk of developing colorectal neoplasm is essential for personalized colorectal cancer (CRC) screening. We developed models to determine relative and absolute risks of colorectal neoplasm based on lifestyle and genetic variants and to validate their application in...

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Detalles Bibliográficos
Autores principales:	Chen, Hongda, Liu, Li, Lu, Ming, Zhang, Yuhan, Lu, Bin, Zhu, Ying, Tian, Jianbo, Li, Xinying, Nie, Shaofa, Miao, Xiaoping, Dai, Min
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Molecular Biosciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8324207/ https://www.ncbi.nlm.nih.gov/pubmed/34336927 http://dx.doi.org/10.3389/fmolb.2021.685410

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