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“Bucket brigade” using lysine residues in RNA-dependent RNA polymerase of SARS-CoV-2
The RNA-dependent RNA polymerase (RdRp) of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a promising drug target for coronavirus disease 2019 (COVID-19) because it plays the most important role in the replication of the RNA genome. Nucleotide analogs such as remdesivir and favipira...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Biophysical Society
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8324383/ https://www.ncbi.nlm.nih.gov/pubmed/34339634 http://dx.doi.org/10.1016/j.bpj.2021.07.026 |