Severe COVID-19 Is Characterized by an Impaired Type I Interferon Response and Elevated Levels of Arginase Producing Granulocytic Myeloid Derived Suppressor Cells

COVID-19 ranges from asymptomatic in 35% of cases to severe in 20% of patients. Differences in the type and degree of inflammation appear to determine the severity of the disease. Recent reports show an increase in circulating monocytic-myeloid-derived suppressor cells (M-MDSC) in severe COVID 19 th...

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Detalles Bibliográficos
Autores principales: Dean, Matthew J., Ochoa, Juan B., Sanchez-Pino, Maria Dulfary, Zabaleta, Jovanny, Garai, Jone, Del Valle, Luis, Wyczechowska, Dorota, Baiamonte, Lyndsey Buckner, Philbrook, Phaethon, Majumder, Rinku, Vander Heide, Richard S., Dunkenberger, Logan, Thylur, Ramesh Puttalingaiah, Nossaman, Bobby, Roberts, W. Mark, Chapple, Andrew G., Wu, Jiande, Hicks, Chindo, Collins, Jack, Luke, Brian, Johnson, Randall, Koul, Hari K., Rees, Chris A., Morris, Claudia R., Garcia-Diaz, Julia, Ochoa, Augusto C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8324422/
https://www.ncbi.nlm.nih.gov/pubmed/34341659
http://dx.doi.org/10.3389/fimmu.2021.695972

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8324422/
https://www.ncbi.nlm.nih.gov/pubmed/34341659
http://dx.doi.org/10.3389/fimmu.2021.695972

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