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Antibodies from malaria-exposed Malians generally interact additively or synergistically with human vaccine-induced RH5 antibodies

Reticulocyte-binding protein homolog 5 (RH5) is a leading Plasmodium falciparum blood-stage vaccine candidate. Another possible candidate, apical membrane antigen 1 (AMA1), was not efficacious in malaria-endemic populations, likely due to pre-existing antimalarial antibodies that interfered with the...

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Detalles Bibliográficos
Autores principales: Willcox, Alexandra C., Huber, Alex S., Diouf, Ababacar, Barrett, Jordan R., Silk, Sarah E., Pulido, David, King, Lloyd D.W., Alanine, Daniel G.W., Minassian, Angela M., Diakite, Mahamadou, Draper, Simon J., Long, Carole A., Miura, Kazutoyo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8324462/
https://www.ncbi.nlm.nih.gov/pubmed/34337556
http://dx.doi.org/10.1016/j.xcrm.2021.100326