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Antibodies from malaria-exposed Malians generally interact additively or synergistically with human vaccine-induced RH5 antibodies
Reticulocyte-binding protein homolog 5 (RH5) is a leading Plasmodium falciparum blood-stage vaccine candidate. Another possible candidate, apical membrane antigen 1 (AMA1), was not efficacious in malaria-endemic populations, likely due to pre-existing antimalarial antibodies that interfered with the...
Autores principales: | Willcox, Alexandra C., Huber, Alex S., Diouf, Ababacar, Barrett, Jordan R., Silk, Sarah E., Pulido, David, King, Lloyd D.W., Alanine, Daniel G.W., Minassian, Angela M., Diakite, Mahamadou, Draper, Simon J., Long, Carole A., Miura, Kazutoyo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8324462/ https://www.ncbi.nlm.nih.gov/pubmed/34337556 http://dx.doi.org/10.1016/j.xcrm.2021.100326 |
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