Toxin import through the antibiotic efflux channel TolC

Bacteria often secrete diffusible protein toxins (bacteriocins) to kill bystander cells during interbacterial competition. Here, we use biochemical, biophysical and structural analyses to show how a bacteriocin exploits TolC, a major outer-membrane antibiotic efflux channel in Gram-negative bacteria...

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Detalles Bibliográficos
Autores principales: Housden, Nicholas G., Webby, Melissa N., Lowe, Edward D., El-Baba, Tarick J., Kaminska, Renata, Redfield, Christina, Robinson, Carol V., Kleanthous, Colin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8324772/
https://www.ncbi.nlm.nih.gov/pubmed/34330923
http://dx.doi.org/10.1038/s41467-021-24930-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8324772/
https://www.ncbi.nlm.nih.gov/pubmed/34330923
http://dx.doi.org/10.1038/s41467-021-24930-y

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