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Stress-primed secretory autophagy promotes extracellular BDNF maturation by enhancing MMP9 secretion
The stress response is an essential mechanism for maintaining homeostasis, and its disruption is implicated in several psychiatric disorders. On the cellular level, stress activates, among other mechanisms, autophagy that regulates homeostasis through protein degradation and recycling. Secretory aut...
Autores principales: | Martinelli, Silvia, Anderzhanova, Elmira A., Bajaj, Thomas, Wiechmann, Svenja, Dethloff, Frederik, Weckmann, Katja, Heinz, Daniel E., Ebert, Tim, Hartmann, Jakob, Geiger, Thomas M., Döngi, Michael, Hafner, Kathrin, Pöhlmann, Max L., Jollans, Lee, Philipsen, Alexandra, Schmidt, Susanne V., Schmidt, Ulrike, Maccarrone, Giuseppina, Stein, Valentin, Hausch, Felix, Turck, Christoph W., Schmidt, Mathias V., Gellner, Anne-Kathrin, Kuster, Bernhard, Gassen, Nils C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8324795/ https://www.ncbi.nlm.nih.gov/pubmed/34330919 http://dx.doi.org/10.1038/s41467-021-24810-5 |
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