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Structural basis for +1 ribosomal frameshifting during EF-G-catalyzed translocation
Frameshifting of mRNA during translation provides a strategy to expand the coding repertoire of cells and viruses. How and where in the elongation cycle +1-frameshifting occurs remains poorly understood. We describe seven ~3.5-Å-resolution cryo-EM structures of 70S ribosome complexes, allowing visua...
Autores principales: | Demo, Gabriel, Gamper, Howard B., Loveland, Anna B., Masuda, Isao, Carbone, Christine E., Svidritskiy, Egor, Hou, Ya-Ming, Korostelev, Andrei A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8324841/ https://www.ncbi.nlm.nih.gov/pubmed/34330903 http://dx.doi.org/10.1038/s41467-021-24911-1 |
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