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Sirtuin 5 depletion impairs mitochondrial function in human proximal tubular epithelial cells

Ischemia is a major cause of kidney damage. Proximal tubular epithelial cells (PTECs) are highly susceptible to ischemic insults that frequently cause acute kidney injury (AKI), a potentially life-threatening condition with high mortality. Accumulating evidence has identified altered mitochondrial f...

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Detalles Bibliográficos
Autores principales:	Haschler, Timo N., Horsley, Harry, Balys, Monika, Anderson, Glenn, Taanman, Jan-Willem, Unwin, Robert J., Norman, Jill T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8324880/ https://www.ncbi.nlm.nih.gov/pubmed/34330933 http://dx.doi.org/10.1038/s41598-021-94185-6

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