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Microglia modulate stable wakefulness via the thalamic reticular nucleus in mice

Microglia are important for brain homeostasis and immunity, but their role in regulating vigilance remains unclear. We employed genetic, physiological, and metabolomic methods to examine microglial involvement in the regulation of wakefulness and sleep. Microglial depletion decreased stable nighttim...

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Detalles Bibliográficos
Autores principales: Liu, Hanxiao, Wang, Xinxing, Chen, Lu, Chen, Liang, Tsirka, Stella E., Ge, Shaoyu, Xiong, Qiaojie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8324895/
https://www.ncbi.nlm.nih.gov/pubmed/34330901
http://dx.doi.org/10.1038/s41467-021-24915-x