Identification of non-classical hCA XII inhibitors using combination of computational approaches for drug design and discovery

Human carbonic anhydrase XII (hCA XII) isozyme is of high therapeutic value as a pharmacological target and biomarker for different types of cancer. The hCA XII is one of the crucial effectors that regulates extracellular and intracellular pH and affects cancer cell proliferation, invasion, growth a...

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Detalles Bibliográficos
Autores principales: Al-Sanea, Mohammad M., Chilingaryan, Garri, Abelyan, Narek, Arakelov, Grigor, Sahakyan, Harutyun, Arakelov, Vahram G., Nazaryan, Karen, Hussein, Shaimaa, Alazmi, Gharam M., Alsharari, Haifa E., Al-faraj, Waad M., Alruwaili, Faten S., Albilasi, Nouf Q., Alsharari, Tahani S., Alsaleh, Abdulaziz A. S., Alazmi, Turki M., Almalki, Atiah H., Alotaibi, Nasser H., Abdelgawad, Mohamed A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8324906/
https://www.ncbi.nlm.nih.gov/pubmed/34330958
http://dx.doi.org/10.1038/s41598-021-94809-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8324906/
https://www.ncbi.nlm.nih.gov/pubmed/34330958
http://dx.doi.org/10.1038/s41598-021-94809-x

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