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CRISPR/Cas9-engineered Drosophila knock-in models to study VCP diseases

Mutations in Valosin Containing Protein (VCP) are associated with several degenerative diseases, including multisystem proteinopathy (MSP-1) and amyotrophic lateral sclerosis. However, patients with VCP mutations vary widely in their pathology and clinical penetrance, making it difficult to devise e...

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Detalles Bibliográficos
Autores principales:	Wall, Jordan M., Basu, Ankita, Zunica, Elizabeth R. M., Dubuisson, Olga S., Pergola, Kathryn, Broussard, Joshua P., Kirwan, John P., Axelrod, Christopher L., Johnson, Alyssa E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Company of Biologists Ltd 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8325010/ https://www.ncbi.nlm.nih.gov/pubmed/34160014 http://dx.doi.org/10.1242/dmm.048603

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