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Acute type B aortic dissection in a pregnant woman with undiagnosed Marfan syndrome: A case report and review of the literature

Aortic dissection during pregnancy is rare but can be life-threatening to both the mother and the foetus. Marfan syndrome is a major risk factor for acute aortic dissection during pregnancy. Here, we present the case of a woman who had not been diagnosed with Marfan syndrome prior to pregnancy and w...

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Autores principales: Miyazaki, Yumiko, Orisaka, Makoto, Kato, Masataka, Kawamura, Hiroshi, Kurokawa, Tetsuji, Yoshida, Yoshio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8325095/
https://www.ncbi.nlm.nih.gov/pubmed/34354931
http://dx.doi.org/10.1016/j.crwh.2021.e00342
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author Miyazaki, Yumiko
Orisaka, Makoto
Kato, Masataka
Kawamura, Hiroshi
Kurokawa, Tetsuji
Yoshida, Yoshio
author_facet Miyazaki, Yumiko
Orisaka, Makoto
Kato, Masataka
Kawamura, Hiroshi
Kurokawa, Tetsuji
Yoshida, Yoshio
author_sort Miyazaki, Yumiko
collection PubMed
description Aortic dissection during pregnancy is rare but can be life-threatening to both the mother and the foetus. Marfan syndrome is a major risk factor for acute aortic dissection during pregnancy. Here, we present the case of a woman who had not been diagnosed with Marfan syndrome prior to pregnancy and who developed acute type B dissection at 32 weeks of gestation. The maternal hemodynamic status was stable, and foetal well-being was ensured. However, under conservative treatment, the dissection extended to the descending aorta, reaching the bilateral iliac artery 2 days later. Due to foetal distress, preterm delivery was performed via caesarean section. The primary treatment of type B aortic dissection is conservative medical treatment, with the goals of hemodynamic stabilisation, minimising the extent of the dissection and decreasing the risk of rupture. However, type B aortic dissection, even the uncomplicated type, in pregnant women may require early and aggressive obstetric interventions to improve maternal and foetal prognoses.
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spelling pubmed-83250952021-08-04 Acute type B aortic dissection in a pregnant woman with undiagnosed Marfan syndrome: A case report and review of the literature Miyazaki, Yumiko Orisaka, Makoto Kato, Masataka Kawamura, Hiroshi Kurokawa, Tetsuji Yoshida, Yoshio Case Rep Womens Health Article Aortic dissection during pregnancy is rare but can be life-threatening to both the mother and the foetus. Marfan syndrome is a major risk factor for acute aortic dissection during pregnancy. Here, we present the case of a woman who had not been diagnosed with Marfan syndrome prior to pregnancy and who developed acute type B dissection at 32 weeks of gestation. The maternal hemodynamic status was stable, and foetal well-being was ensured. However, under conservative treatment, the dissection extended to the descending aorta, reaching the bilateral iliac artery 2 days later. Due to foetal distress, preterm delivery was performed via caesarean section. The primary treatment of type B aortic dissection is conservative medical treatment, with the goals of hemodynamic stabilisation, minimising the extent of the dissection and decreasing the risk of rupture. However, type B aortic dissection, even the uncomplicated type, in pregnant women may require early and aggressive obstetric interventions to improve maternal and foetal prognoses. Elsevier 2021-07-16 /pmc/articles/PMC8325095/ /pubmed/34354931 http://dx.doi.org/10.1016/j.crwh.2021.e00342 Text en © 2021 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Article
Miyazaki, Yumiko
Orisaka, Makoto
Kato, Masataka
Kawamura, Hiroshi
Kurokawa, Tetsuji
Yoshida, Yoshio
Acute type B aortic dissection in a pregnant woman with undiagnosed Marfan syndrome: A case report and review of the literature
title Acute type B aortic dissection in a pregnant woman with undiagnosed Marfan syndrome: A case report and review of the literature
title_full Acute type B aortic dissection in a pregnant woman with undiagnosed Marfan syndrome: A case report and review of the literature
title_fullStr Acute type B aortic dissection in a pregnant woman with undiagnosed Marfan syndrome: A case report and review of the literature
title_full_unstemmed Acute type B aortic dissection in a pregnant woman with undiagnosed Marfan syndrome: A case report and review of the literature
title_short Acute type B aortic dissection in a pregnant woman with undiagnosed Marfan syndrome: A case report and review of the literature
title_sort acute type b aortic dissection in a pregnant woman with undiagnosed marfan syndrome: a case report and review of the literature
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8325095/
https://www.ncbi.nlm.nih.gov/pubmed/34354931
http://dx.doi.org/10.1016/j.crwh.2021.e00342
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