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Accelerated expansion of pathogenic mitochondrial DNA heteroplasmies in Huntington’s disease
Mitochondrial dysfunction is found in the brain and peripheral tissues of patients diagnosed with Huntington’s disease (HD), an irreversible neurodegenerative disease of which aging is a major risk factor. Mitochondrial function is encoded by not only nuclear DNA but also DNA within mitochondria (mt...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8325154/ https://www.ncbi.nlm.nih.gov/pubmed/34301881 http://dx.doi.org/10.1073/pnas.2014610118 |