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β-acetoxyisovaleryl alkannin (AAN-II) from Alkanna tinctoria promotes the healing of pressure-induced venous ulcers in a rabbit model through the activation of TGF-β/Smad3 signaling

Alkannin-based pharmaceutical formulations for improving wound healing have been on the market for several years. However, detailed molecular mechanisms of their action have yet to be elucidated. Here, we investigated the potential roles of AAN-II in improving the healing of pressure-induced venous...

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Detalles Bibliográficos
Autores principales: Yang, Xiao, Fan, Weijing, Huang, Renyan, Liu, Guobin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8325215/
https://www.ncbi.nlm.nih.gov/pubmed/34332546
http://dx.doi.org/10.1186/s11658-021-00278-5